Abstract
The focus of developmental biologists has expanded from the analysis of gene expression to include the analysis of cell signalling. Heterotrimeric G proteins (G proteins) mediate signalling from a superfamily of heptahelical receptors (G-protein-coupled receptors) to a smaller number of effector units that include adenylyl cyclases, phospholipase C and various ion channels. The convergence of developmental biology with cell signalling has now revealed overlaps in which G proteins mediate complex pathways in embryonic development.
| Original language | English |
|---|---|
| Pages (from-to) | 689-701 |
| Number of pages | 13 |
| Journal | Nature Reviews Molecular Cell Biology |
| Volume | 6 |
| Issue number | 9 |
| DOIs | |
| State | Published - Sep 2005 |
Fingerprint
Dive into the research topics of 'G proteins in development'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver