Gel point determination of biopolymer based semi-IPN hydrogels

Soumitra Choudhary; Surita R. Bhatia

doi:10.1063/1.2964760

Gel point determination of biopolymer based semi-IPN hydrogels

Soumitra Choudhary
, Surita R. Bhatia

Chemistry

University of Massachusetts

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Water-based semi-IPNs (Interpenetrating Polymer Networks) were prepared by mixing two biopolymers, alginate and hydrophobically modified ethylhydroxy ethyl cellulose (HMEHEC), followed by crosslinking the alginate by in-situ release of calcium ions. By altering two different parameters, molecular weight of HMEHEC and calcium crosslinker concentration, we were able to fine tune the rheological properties of the semi-IPNs. Rheological studies in the linear viscoelastic region indicate storage moduli comparable to soft tissue for hydrogels having 90 wt% water. The system is found to be stable over a prolonged period of time, i.e. no phase separation is observed. Uniformity of the structure is confirmed by monotonic behavior of the intensity-q slope in SAXS and SANS over the entire length scale.

Original language	English
Title of host publication	The XVth International Congress on Rheology - The Society of Rheology 80th Annual Meeting
Pages	549-551
Number of pages	3
DOIs	https://doi.org/10.1063/1.2964760
State	Published - 2008
Event	15th International Congress on Rheology - Monterey, CA, United States Duration: Aug 3 2008 → Aug 8 2008

Publication series

Name	AIP Conference Proceedings
Volume	1027
ISSN (Print)	0094-243X
ISSN (Electronic)	1551-7616

Conference

Conference	15th International Congress on Rheology
Country/Territory	United States
City	Monterey, CA
Period	08/3/08 → 08/8/08

Keywords

Alginate
Hydrogels
Hydrophobically modified ethyl hydroxyl ethyl cellulose
Interpenetrating polymer networks

Access to Document

10.1063/1.2964760

Cite this

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title = "Gel point determination of biopolymer based semi-IPN hydrogels",

abstract = "Water-based semi-IPNs (Interpenetrating Polymer Networks) were prepared by mixing two biopolymers, alginate and hydrophobically modified ethylhydroxy ethyl cellulose (HMEHEC), followed by crosslinking the alginate by in-situ release of calcium ions. By altering two different parameters, molecular weight of HMEHEC and calcium crosslinker concentration, we were able to fine tune the rheological properties of the semi-IPNs. Rheological studies in the linear viscoelastic region indicate storage moduli comparable to soft tissue for hydrogels having 90 wt\% water. The system is found to be stable over a prolonged period of time, i.e. no phase separation is observed. Uniformity of the structure is confirmed by monotonic behavior of the intensity-q slope in SAXS and SANS over the entire length scale.",

keywords = "Alginate, Hydrogels, Hydrophobically modified ethyl hydroxyl ethyl cellulose, Interpenetrating polymer networks",

author = "Soumitra Choudhary and Bhatia, \{Surita R.\}",

year = "2008",

doi = "10.1063/1.2964760",

language = "English",

isbn = "9780735405493",

series = "AIP Conference Proceedings",

pages = "549--551",

booktitle = "The XVth International Congress on Rheology - The Society of Rheology 80th Annual Meeting",

note = "15th International Congress on Rheology ; Conference date: 03-08-2008 Through 08-08-2008",

}

TY - GEN

T1 - Gel point determination of biopolymer based semi-IPN hydrogels

AU - Choudhary, Soumitra

AU - Bhatia, Surita R.

PY - 2008

Y1 - 2008

N2 - Water-based semi-IPNs (Interpenetrating Polymer Networks) were prepared by mixing two biopolymers, alginate and hydrophobically modified ethylhydroxy ethyl cellulose (HMEHEC), followed by crosslinking the alginate by in-situ release of calcium ions. By altering two different parameters, molecular weight of HMEHEC and calcium crosslinker concentration, we were able to fine tune the rheological properties of the semi-IPNs. Rheological studies in the linear viscoelastic region indicate storage moduli comparable to soft tissue for hydrogels having 90 wt% water. The system is found to be stable over a prolonged period of time, i.e. no phase separation is observed. Uniformity of the structure is confirmed by monotonic behavior of the intensity-q slope in SAXS and SANS over the entire length scale.

AB - Water-based semi-IPNs (Interpenetrating Polymer Networks) were prepared by mixing two biopolymers, alginate and hydrophobically modified ethylhydroxy ethyl cellulose (HMEHEC), followed by crosslinking the alginate by in-situ release of calcium ions. By altering two different parameters, molecular weight of HMEHEC and calcium crosslinker concentration, we were able to fine tune the rheological properties of the semi-IPNs. Rheological studies in the linear viscoelastic region indicate storage moduli comparable to soft tissue for hydrogels having 90 wt% water. The system is found to be stable over a prolonged period of time, i.e. no phase separation is observed. Uniformity of the structure is confirmed by monotonic behavior of the intensity-q slope in SAXS and SANS over the entire length scale.

KW - Alginate

KW - Hydrogels

KW - Hydrophobically modified ethyl hydroxyl ethyl cellulose

KW - Interpenetrating polymer networks

UR - https://www.scopus.com/pages/publications/51149097745

U2 - 10.1063/1.2964760

DO - 10.1063/1.2964760

M3 - Conference contribution

AN - SCOPUS:51149097745

SN - 9780735405493

T3 - AIP Conference Proceedings

SP - 549

EP - 551

BT - The XVth International Congress on Rheology - The Society of Rheology 80th Annual Meeting

T2 - 15th International Congress on Rheology

Y2 - 3 August 2008 through 8 August 2008

ER -

Gel point determination of biopolymer based semi-IPN hydrogels

Abstract

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Keywords

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