Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

Pierre Abad; Jérôme Gouzy; Jean Marc Aury; Philippe Castagnone-Sereno; Etienne G.J. Danchin; Emeline Deleury; Laetitia Perfus-Barbeoch; Véronique Anthouard; François Artiguenave; Vivian C. Blok; Marie Cécile Caillaud; Pedro M. Coutinho; Corinne Dasilva; Francesca De Luca; Florence Deau; Magali Esquibet; Timothé Flutre; Jared V. Goldstone; Noureddine Hamamouch; Tarek Hewezi; Olivier Jaillon; Claire Jubin; Paola Leonetti; Marc Magliano; Tom R. Maier; Gabriel V. Markov; Paul McVeigh; Graziano Pesole; Julie Poulain; Marc Robinson-Rechavi; Erika Sallet; Béatrice Ségurens; Delphine Steinbach; Tom Tytgat; Edgardo Ugarte; Cyril Van Ghelder; Pasqua Veronico; Thomas J. Baum; Mark Blaxter; Teresa Bleve-Zacheo; Eric L. Davis; Jonathan J. Ewbank; Bruno Favery; Eric Grenier; Bernard Henrissat; John T. Jones; Vincent Laudet; Aaron G. Maule; Hadi Quesneville; Marie Noëlle Rosso; Thomas Schiex; Geert Smant; Jean Weissenbach; Patrick Wincker

doi:10.1038/nbt.1482

Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

Pierre Abad
, Jérôme Gouzy
, Jean Marc Aury
, Philippe Castagnone-Sereno
, Etienne G.J. Danchin
, Emeline Deleury
, Laetitia Perfus-Barbeoch
, Véronique Anthouard
, François Artiguenave
, Vivian C. Blok
, Marie Cécile Caillaud
, Pedro M. Coutinho
, Corinne Dasilva
, Francesca De Luca
, Florence Deau
, Magali Esquibet
, Timothé Flutre
, Jared V. Goldstone
, Noureddine Hamamouch
, Tarek Hewezi

Olivier Jaillon, Claire Jubin, Paola Leonetti, Marc Magliano, Tom R. Maier, Gabriel V. Markov, Paul McVeigh, Graziano Pesole, Julie Poulain, Marc Robinson-Rechavi, Erika Sallet, Béatrice Ségurens, Delphine Steinbach, Tom Tytgat, Edgardo Ugarte, Cyril Van Ghelder, Pasqua Veronico, Thomas J. Baum, Mark Blaxter, Teresa Bleve-Zacheo, Eric L. Davis, Jonathan J. Ewbank, Bruno Favery, Eric Grenier, Bernard Henrissat, John T. Jones, Vincent Laudet, Aaron G. Maule, Hadi Quesneville, Marie Noëlle Rosso, Thomas Schiex, Geert Smant, Jean Weissenbach, Patrick Wincker

Biochemistry and Cell Biology

INRAE
CNRS
UMR 1301
UMR 441-2594
Commissariat à l’énergie atomique et aux énergies alternatives
Université d'Evry Val d'Essonne
The James Hutton Institute
Aix-Marseille Université
National Research Council of Italy
Institut Agro / Inrae / Ifremer
UR1164 Unité de Recherche en Génomique et Informatique (URGI)
Woods Hole Oceanographic Institution
Iowa State University
Université de Lyon
Muséum national d'histoire naturelle
Queen's University Belfast
University of Bari
University of Lausanne
Swiss Institute of Bioinformatics
GENOPOLE
Wageningen University & Research
University of Edinburgh
North Carolina State University
Institut national de la santé et de la recherche médicale

Research output: Contribution to journal › Article › peer-review

1086 Scopus citations

Abstract

Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.

Original language	English
Pages (from-to)	909-915
Number of pages	7
Journal	Nature Biotechnology
Volume	26
Issue number	8
DOIs	https://doi.org/10.1038/nbt.1482
State	Published - Aug 2008

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10.1038/nbt.1482

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Abad, P., Gouzy, J., Aury, J. M., Castagnone-Sereno, P., Danchin, E. G. J., Deleury, E., Perfus-Barbeoch, L., Anthouard, V., Artiguenave, F., Blok, V. C., Caillaud, M. C., Coutinho, P. M., Dasilva, C., De Luca, F., Deau, F., Esquibet, M., Flutre, T., Goldstone, J. V., Hamamouch, N., ... Wincker, P. (2008). Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita. Nature Biotechnology, 26(8), 909-915. https://doi.org/10.1038/nbt.1482

@article{5974c02fa9fe409aa338b54393e0c97e,

title = "Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita",

abstract = "Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.",

author = "Pierre Abad and J{\'e}r{\^o}me Gouzy and Aury, \{Jean Marc\} and Philippe Castagnone-Sereno and Danchin, \{Etienne G.J.\} and Emeline Deleury and Laetitia Perfus-Barbeoch and V{\'e}ronique Anthouard and Fran{\c c}ois Artiguenave and Blok, \{Vivian C.\} and Caillaud, \{Marie C{\'e}cile\} and Coutinho, \{Pedro M.\} and Corinne Dasilva and \{De Luca\}, Francesca and Florence Deau and Magali Esquibet and Timoth{\'e} Flutre and Goldstone, \{Jared V.\} and Noureddine Hamamouch and Tarek Hewezi and Olivier Jaillon and Claire Jubin and Paola Leonetti and Marc Magliano and Maier, \{Tom R.\} and Markov, \{Gabriel V.\} and Paul McVeigh and Graziano Pesole and Julie Poulain and Marc Robinson-Rechavi and Erika Sallet and B{\'e}atrice S{\'e}gurens and Delphine Steinbach and Tom Tytgat and Edgardo Ugarte and \{Van Ghelder\}, Cyril and Pasqua Veronico and Baum, \{Thomas J.\} and Mark Blaxter and Teresa Bleve-Zacheo and Davis, \{Eric L.\} and Ewbank, \{Jonathan J.\} and Bruno Favery and Eric Grenier and Bernard Henrissat and Jones, \{John T.\} and Vincent Laudet and Maule, \{Aaron G.\} and Hadi Quesneville and Rosso, \{Marie No{\"e}lle\} and Thomas Schiex and Geert Smant and Jean Weissenbach and Patrick Wincker",

year = "2008",

month = aug,

doi = "10.1038/nbt.1482",

language = "English",

volume = "26",

pages = "909--915",

journal = "Nature Biotechnology",

issn = "1087-0156",

number = "8",

}

Abad, P, Gouzy, J, Aury, JM, Castagnone-Sereno, P, Danchin, EGJ, Deleury, E, Perfus-Barbeoch, L, Anthouard, V, Artiguenave, F, Blok, VC, Caillaud, MC, Coutinho, PM, Dasilva, C, De Luca, F, Deau, F, Esquibet, M, Flutre, T, Goldstone, JV, Hamamouch, N, Hewezi, T, Jaillon, O, Jubin, C, Leonetti, P, Magliano, M, Maier, TR, Markov, GV, McVeigh, P, Pesole, G, Poulain, J, Robinson-Rechavi, M, Sallet, E, Ségurens, B, Steinbach, D, Tytgat, T, Ugarte, E, Van Ghelder, C, Veronico, P, Baum, TJ, Blaxter, M, Bleve-Zacheo, T, Davis, EL, Ewbank, JJ, Favery, B, Grenier, E, Henrissat, B, Jones, JT, Laudet, V, Maule, AG, Quesneville, H, Rosso, MN, Schiex, T, Smant, G, Weissenbach, J & Wincker, P 2008, 'Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita', Nature Biotechnology, vol. 26, no. 8, pp. 909-915. https://doi.org/10.1038/nbt.1482

TY - JOUR

T1 - Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

AU - Abad, Pierre

AU - Gouzy, Jérôme

AU - Aury, Jean Marc

AU - Castagnone-Sereno, Philippe

AU - Danchin, Etienne G.J.

AU - Deleury, Emeline

AU - Perfus-Barbeoch, Laetitia

AU - Anthouard, Véronique

AU - Artiguenave, François

AU - Blok, Vivian C.

AU - Caillaud, Marie Cécile

AU - Coutinho, Pedro M.

AU - Dasilva, Corinne

AU - De Luca, Francesca

AU - Deau, Florence

AU - Esquibet, Magali

AU - Flutre, Timothé

AU - Goldstone, Jared V.

AU - Hamamouch, Noureddine

AU - Hewezi, Tarek

AU - Jaillon, Olivier

AU - Jubin, Claire

AU - Leonetti, Paola

AU - Magliano, Marc

AU - Maier, Tom R.

AU - Markov, Gabriel V.

AU - McVeigh, Paul

AU - Pesole, Graziano

AU - Poulain, Julie

AU - Robinson-Rechavi, Marc

AU - Sallet, Erika

AU - Ségurens, Béatrice

AU - Steinbach, Delphine

AU - Tytgat, Tom

AU - Ugarte, Edgardo

AU - Van Ghelder, Cyril

AU - Veronico, Pasqua

AU - Baum, Thomas J.

AU - Blaxter, Mark

AU - Bleve-Zacheo, Teresa

AU - Davis, Eric L.

AU - Ewbank, Jonathan J.

AU - Favery, Bruno

AU - Grenier, Eric

AU - Henrissat, Bernard

AU - Jones, John T.

AU - Laudet, Vincent

AU - Maule, Aaron G.

AU - Quesneville, Hadi

AU - Rosso, Marie Noëlle

AU - Schiex, Thomas

AU - Smant, Geert

AU - Weissenbach, Jean

AU - Wincker, Patrick

PY - 2008/8

Y1 - 2008/8

N2 - Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.

AB - Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.

UR - https://www.scopus.com/pages/publications/49449094873

U2 - 10.1038/nbt.1482

DO - 10.1038/nbt.1482

M3 - Article

C2 - 18660804

AN - SCOPUS:49449094873

SN - 1087-0156

VL - 26

SP - 909

EP - 915

JO - Nature Biotechnology

JF - Nature Biotechnology

IS - 8

ER -

Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

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