Skip to main navigation Skip to search Skip to main content

HIgh-throughput integrated single-cell transcriptomic and proteomic analysis

  • California Institute of Technology

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We present a new technology that measures both transcriptome and proteome from the same single cells. This technology was validated using T cells and thereafter was applied to embryonic stem cells (ESCs) to understand how ESCs maintain pluripotency and proliferation while they are cultured in the colony format. Through transcription network analysis, we discovered a cohort of genes promoting selfrenewal and secretion of growth factors.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages1491-1493
Number of pages3
ISBN (Electronic)9780979806476
StatePublished - 2014
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: Oct 26 2014Oct 30 2014

Publication series

Name18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Conference

Conference18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Country/TerritoryUnited States
CitySan Antonio
Period10/26/1410/30/14

Keywords

  • Embryonic stem cells
  • Proteome
  • Single cell analysis
  • Transcriptome

Fingerprint

Dive into the research topics of 'HIgh-throughput integrated single-cell transcriptomic and proteomic analysis'. Together they form a unique fingerprint.

Cite this