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Image analysis for automated assessment of grade of neuroblastic differentiation

  • Jun Kong
  • , Hiroyuki Shimada
  • , Kim Boyer
  • , Joel Saltz
  • , Metin Gurcan
  • Ohio State University
  • University of Southern California

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

28 Scopus citations

Abstract

Peripheral Neuroblastic Tumors (pNTs) make the most commonly encountered tumor groups in children. Neuroblastoma, one of the categories in pNTs, is known to have unique biological behaviors with variable clinical prognoses of the patients. Part of the neuroblastoma prognosis is closely related with grade of neuroblastic differentiation. In this work, we present an automatic classification system that includes a novel segmentation method using the EM algorithm with the Fisher-Rao criterion as its kernel. This is followed by a classification stage with classifiers applied to the actual neuroblastoma images. The good classification accuracy suggests that the developed method is promising in automating this pathological assessment.

Original languageEnglish
Title of host publication2007 4th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro - Proceedings
Pages61-64
Number of pages4
DOIs
StatePublished - 2007
Event2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07 - Arlington, VA, United States
Duration: Apr 12 2007Apr 15 2007

Publication series

Name2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings

Conference

Conference2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07
Country/TerritoryUnited States
CityArlington, VA
Period04/12/0704/15/07

Keywords

  • Color space
  • Image segmentation
  • Neuroblastic differentiation
  • Neuroblastoma
  • Pattern classification

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