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Image registration with optimal regularization parameter selection by learned auto encoder features

  • Georgia State University
  • Universidade Federal de Minas Gerais
  • Emory University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

In this paper, we propose a method that optimizes a regularization parameter for the regularized Free Form Deformation (FFD) non-rigid image registration. The developed process utilizes autoencoder generated image representations to assess image data generalization quality by the regularization parameter. Both pixel intensity and learned features are used to improve the overall accuracy and regularity of the resulting inverse problem solution. We implement the new selection criterion with its use in the non-rigid image FFD registration based on multi-level Bspline with L2-regularization, and validate the method with synthetic and real histopathology image datasets. Both qualitative and quantitative results suggest the efficacy of our developed method for fine-tuning histopathology microscope images.

Original languageEnglish
Title of host publication2021 IEEE 18th International Symposium on Biomedical Imaging, ISBI 2021
PublisherIEEE Computer Society
Pages702-705
Number of pages4
ISBN (Electronic)9781665412469
DOIs
StatePublished - Apr 13 2021
Event18th IEEE International Symposium on Biomedical Imaging, ISBI 2021 - Virtual, Online, France
Duration: Apr 13 2021Apr 16 2021

Publication series

NameProceedings - International Symposium on Biomedical Imaging
Volume2021-April
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Conference

Conference18th IEEE International Symposium on Biomedical Imaging, ISBI 2021
Country/TerritoryFrance
CityVirtual, Online
Period04/13/2104/16/21

Keywords

  • Autoencoder
  • Bspline
  • Free form deformation
  • Image registration
  • Inverse problems
  • Whole slide image

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