Imaging the Neurochemistry of Alcohol and Substance Abuse

Diana Martinez; Jong Hoon Kim; John Krystal; Anissa Abi-Dargham

doi:10.1016/j.nic.2007.07.004

Imaging the Neurochemistry of Alcohol and Substance Abuse

Diana Martinez
, Jong Hoon Kim
, John Krystal
, Anissa Abi-Dargham

Psychiatry

Columbia University
Yale University

Research output: Contribution to journal › Review article › peer-review

49 Scopus citations

Abstract

Animal models of abuse and dependence have long suggested that chronic drug and alcohol exposure is associated with marked changes in neurochemistry. The development of PET and SPECT imaging now allows investigation of the effects of addiction on the neurochemistry of the human brain. This article reviews the literature of radiochemical imaging in cocaine, alcohol, heroin, methamphetamine, MDMA, and ketamine abuse and dependence.

Original language	English
Pages (from-to)	539-555
Number of pages	17
Journal	Neuroimaging Clinics of North America
Volume	17
Issue number	4
DOIs	https://doi.org/10.1016/j.nic.2007.07.004
State	Published - Nov 2007

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10.1016/j.nic.2007.07.004

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title = "Imaging the Neurochemistry of Alcohol and Substance Abuse",

abstract = "Animal models of abuse and dependence have long suggested that chronic drug and alcohol exposure is associated with marked changes in neurochemistry. The development of PET and SPECT imaging now allows investigation of the effects of addiction on the neurochemistry of the human brain. This article reviews the literature of radiochemical imaging in cocaine, alcohol, heroin, methamphetamine, MDMA, and ketamine abuse and dependence.",

author = "Diana Martinez and Kim, \{Jong Hoon\} and John Krystal and Anissa Abi-Dargham",

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AU - Kim, Jong Hoon

AU - Krystal, John

AU - Abi-Dargham, Anissa

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Y1 - 2007/11

N2 - Animal models of abuse and dependence have long suggested that chronic drug and alcohol exposure is associated with marked changes in neurochemistry. The development of PET and SPECT imaging now allows investigation of the effects of addiction on the neurochemistry of the human brain. This article reviews the literature of radiochemical imaging in cocaine, alcohol, heroin, methamphetamine, MDMA, and ketamine abuse and dependence.

AB - Animal models of abuse and dependence have long suggested that chronic drug and alcohol exposure is associated with marked changes in neurochemistry. The development of PET and SPECT imaging now allows investigation of the effects of addiction on the neurochemistry of the human brain. This article reviews the literature of radiochemical imaging in cocaine, alcohol, heroin, methamphetamine, MDMA, and ketamine abuse and dependence.

UR - https://www.scopus.com/pages/publications/35649019170

U2 - 10.1016/j.nic.2007.07.004

DO - 10.1016/j.nic.2007.07.004

M3 - Review article

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AN - SCOPUS:35649019170

SN - 1052-5149

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SP - 539

EP - 555

JO - Neuroimaging Clinics of North America

JF - Neuroimaging Clinics of North America

IS - 4

ER -

Imaging the Neurochemistry of Alcohol and Substance Abuse

Abstract

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