@inbook{2f8c9650f29c41cab7536ba9ee721394,
title = "In vitro studies of membrane permeability induced by amyloidogenic polypeptides using large unilamellar vesicles",
abstract = "The process of amyloid formation is cytotoxic and contributes to a wide range of human diseases, but the mechanisms of amyloid-induced cytotoxicity are not well understood. It has been proposed that amyloidogenic peptides exert their toxiceffects by damaging membranes. Membrane disruption is clearly not the only mechanism of toxicity, but the literature suggests that loss of membrane integrity may be a contributing factor. In this chapter we describe the measurement of in vitro membrane leakage induced by amyloidogenic proteinsvia the use of model vesicles.",
keywords = "Amyloid, Cytotoxicity, Islet amyloid polypeptide, Membrane disruption, Membrane leakage",
author = "Ping Cao and Raleigh, \{Daniel P.\}",
note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media New York 2016.",
year = "2016",
doi = "10.1007/978-1-4939-2978-8\_18",
language = "English",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "283--290",
booktitle = "Methods in Molecular Biology",
}