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Learning Structured Neural Dynamics from Single Trial Population Recording

  • Josue Nassar
  • , Scott W. Linderman
  • , Yuan Zhao
  • , Monica Bugallo
  • , Il Memming Park
  • Stony Brook University
  • Columbia University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

To understand the complex nonlinear dynamics of neural circuits, we fit a structured state-space model called tree-structured recurrent switching linear dynamical system (TrSLDS) to noisy high-dimensional neural time series. TrSLDS is a multi-scale hierarchical generative model for the state-space dynamics where each node of the latent tree captures locally linear dynamics. TrSLDS can be learned efficiently and in a fully Bayesian manner using Gibbs sampling. We showcase TrSLDS' potential of inferring low-dimensional interpretable dynamical systems on a variety of examples.

Original languageEnglish
Title of host publicationConference Record of the 52nd Asilomar Conference on Signals, Systems and Computers, ACSSC 2018
EditorsMichael B. Matthews
PublisherIEEE Computer Society
Pages666-670
Number of pages5
ISBN (Electronic)9781538692189
DOIs
StatePublished - Jul 2 2018
Event52nd Asilomar Conference on Signals, Systems and Computers, ACSSC 2018 - Pacific Grove, United States
Duration: Oct 28 2018Oct 31 2018

Publication series

NameConference Record - Asilomar Conference on Signals, Systems and Computers
Volume2018-October
ISSN (Print)1058-6393

Conference

Conference52nd Asilomar Conference on Signals, Systems and Computers, ACSSC 2018
Country/TerritoryUnited States
CityPacific Grove
Period10/28/1810/31/18

Keywords

  • Bayesian inference
  • dynamical system
  • population spike trains
  • state-space model
  • statistical neuroscience

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