Lesion assessment and radiation dose in contrast-enhanced digital breast tomosynthesis

Hailiang Huang; David A. Scaduto; Chunling Liu; Jie Yang; Chencan Zhu; Kim Rinaldi; Jason Eisenberg; Jingxuan Liu; Mathias Hoernig; Julia Wicklein; Sebastian Vogt; Thomas Mertelmeier; Paul R. Fisher; Wei Zhao

doi:10.1117/12.2316371

Lesion assessment and radiation dose in contrast-enhanced digital breast tomosynthesis

Hailiang Huang
, David A. Scaduto
, Chunling Liu
, Jie Yang
, Chencan Zhu
, Kim Rinaldi
, Jason Eisenberg
, Jingxuan Liu
, Mathias Hoernig
, Julia Wicklein
, Sebastian Vogt
, Thomas Mertelmeier
, Paul R. Fisher
, Wei Zhao

Dept. of Radiology
and Preventive Medicine
Stony Brook University
Siemens
Siemens Medical Solutions USA

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2 Scopus citations

Abstract

Contrast-Enhanced Digital Breast Tomosynthesis (CEDBT) provides a three-dimensional (3D) contrast-enhancement map with co-registered anatomical information from low-energy DBT. It combines the benefits from Contrast-Enhanced Digital Mammography (CEDM) and Digital Breast Tomosynthesis (DBT), and may improve breast cancer detection and assessment of lesion morphology. We investigate the efficacy of CEDBT in the assessment of lesion contrast enhancement and margin identification, and evaluate the dose efficiency. We generate synthetic CEDM images from CEDBT data, similar to synthesis of 2D mammograms from DBT data, which may facilitate overall lesion assessment without additional radiation dose. Preliminary results from a patient study show that CEDBT depicts lesion margins better compared to CEDM, while the contrast-enhancement level for in-plane slice is not as high as in CEDM. CEDBT delivers less radiation dose compared to CEDM + DBT. Synthetic CEDM is able to provide lesion contrast-enhancement level comparable to CEDM.

Original language	English
Title of host publication	14th International Workshop on Breast Imaging (IWBI 2018)
Editors	Elizabeth A. Krupinski
Publisher	SPIE
ISBN (Electronic)	9781510620070
DOIs	https://doi.org/10.1117/12.2316371
State	Published - 2018
Event	14th International Workshop on Breast Imaging (IWBI 2018) - Atlanta, United States Duration: Jul 8 2018 → Jul 11 2018

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10718
ISSN (Print)	1605-7422

Conference

Conference	14th International Workshop on Breast Imaging (IWBI 2018)
Country/Territory	United States
City	Atlanta
Period	07/8/18 → 07/11/18

Keywords

Contrast Enhanced Digital Breast Tomosynthesis
Contrast Enhanced Digital Mammography
Synthetic contrast enhanced digital mammography

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10.1117/12.2316371

Cite this

Huang, H., Scaduto, D. A., Liu, C., Yang, J., Zhu, C., Rinaldi, K., Eisenberg, J., Liu, J., Hoernig, M., Wicklein, J., Vogt, S., Mertelmeier, T., Fisher, P. R., & Zhao, W. (2018). Lesion assessment and radiation dose in contrast-enhanced digital breast tomosynthesis. In E. A. Krupinski (Ed.), 14th International Workshop on Breast Imaging (IWBI 2018) Article 107181J (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10718). SPIE. https://doi.org/10.1117/12.2316371

@inproceedings{8c283a88599b4c0ba61c299a251b9f8f,

title = "Lesion assessment and radiation dose in contrast-enhanced digital breast tomosynthesis",

abstract = "Contrast-Enhanced Digital Breast Tomosynthesis (CEDBT) provides a three-dimensional (3D) contrast-enhancement map with co-registered anatomical information from low-energy DBT. It combines the benefits from Contrast-Enhanced Digital Mammography (CEDM) and Digital Breast Tomosynthesis (DBT), and may improve breast cancer detection and assessment of lesion morphology. We investigate the efficacy of CEDBT in the assessment of lesion contrast enhancement and margin identification, and evaluate the dose efficiency. We generate synthetic CEDM images from CEDBT data, similar to synthesis of 2D mammograms from DBT data, which may facilitate overall lesion assessment without additional radiation dose. Preliminary results from a patient study show that CEDBT depicts lesion margins better compared to CEDM, while the contrast-enhancement level for in-plane slice is not as high as in CEDM. CEDBT delivers less radiation dose compared to CEDM + DBT. Synthetic CEDM is able to provide lesion contrast-enhancement level comparable to CEDM.",

keywords = "Contrast Enhanced Digital Breast Tomosynthesis, Contrast Enhanced Digital Mammography, Synthetic contrast enhanced digital mammography",

author = "Hailiang Huang and Scaduto, \{David A.\} and Chunling Liu and Jie Yang and Chencan Zhu and Kim Rinaldi and Jason Eisenberg and Jingxuan Liu and Mathias Hoernig and Julia Wicklein and Sebastian Vogt and Thomas Mertelmeier and Fisher, \{Paul R.\} and Wei Zhao",

note = "Publisher Copyright: {\textcopyright} 2018 SPIE.; 14th International Workshop on Breast Imaging (IWBI 2018) ; Conference date: 08-07-2018 Through 11-07-2018",

year = "2018",

doi = "10.1117/12.2316371",

language = "English",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "SPIE",

editor = "Krupinski, \{Elizabeth A.\}",

booktitle = "14th International Workshop on Breast Imaging (IWBI 2018)",

}

Huang, H, Scaduto, DA, Liu, C, Yang, J, Zhu, C, Rinaldi, K, Eisenberg, J, Liu, J, Hoernig, M, Wicklein, J, Vogt, S, Mertelmeier, T, Fisher, PR & Zhao, W 2018, Lesion assessment and radiation dose in contrast-enhanced digital breast tomosynthesis. in EA Krupinski (ed.), 14th International Workshop on Breast Imaging (IWBI 2018)., 107181J, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10718, SPIE, 14th International Workshop on Breast Imaging (IWBI 2018), Atlanta, United States, 07/8/18. https://doi.org/10.1117/12.2316371

Lesion assessment and radiation dose in contrast-enhanced digital breast tomosynthesis. / Huang, Hailiang; Scaduto, David A.; Liu, Chunling et al.
14th International Workshop on Breast Imaging (IWBI 2018). ed. / Elizabeth A. Krupinski. SPIE, 2018. 107181J (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10718).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Lesion assessment and radiation dose in contrast-enhanced digital breast tomosynthesis

AU - Huang, Hailiang

AU - Scaduto, David A.

AU - Liu, Chunling

AU - Yang, Jie

AU - Zhu, Chencan

AU - Rinaldi, Kim

AU - Eisenberg, Jason

AU - Liu, Jingxuan

AU - Hoernig, Mathias

AU - Wicklein, Julia

AU - Vogt, Sebastian

AU - Mertelmeier, Thomas

AU - Fisher, Paul R.

AU - Zhao, Wei

PY - 2018

Y1 - 2018

N2 - Contrast-Enhanced Digital Breast Tomosynthesis (CEDBT) provides a three-dimensional (3D) contrast-enhancement map with co-registered anatomical information from low-energy DBT. It combines the benefits from Contrast-Enhanced Digital Mammography (CEDM) and Digital Breast Tomosynthesis (DBT), and may improve breast cancer detection and assessment of lesion morphology. We investigate the efficacy of CEDBT in the assessment of lesion contrast enhancement and margin identification, and evaluate the dose efficiency. We generate synthetic CEDM images from CEDBT data, similar to synthesis of 2D mammograms from DBT data, which may facilitate overall lesion assessment without additional radiation dose. Preliminary results from a patient study show that CEDBT depicts lesion margins better compared to CEDM, while the contrast-enhancement level for in-plane slice is not as high as in CEDM. CEDBT delivers less radiation dose compared to CEDM + DBT. Synthetic CEDM is able to provide lesion contrast-enhancement level comparable to CEDM.

AB - Contrast-Enhanced Digital Breast Tomosynthesis (CEDBT) provides a three-dimensional (3D) contrast-enhancement map with co-registered anatomical information from low-energy DBT. It combines the benefits from Contrast-Enhanced Digital Mammography (CEDM) and Digital Breast Tomosynthesis (DBT), and may improve breast cancer detection and assessment of lesion morphology. We investigate the efficacy of CEDBT in the assessment of lesion contrast enhancement and margin identification, and evaluate the dose efficiency. We generate synthetic CEDM images from CEDBT data, similar to synthesis of 2D mammograms from DBT data, which may facilitate overall lesion assessment without additional radiation dose. Preliminary results from a patient study show that CEDBT depicts lesion margins better compared to CEDM, while the contrast-enhancement level for in-plane slice is not as high as in CEDM. CEDBT delivers less radiation dose compared to CEDM + DBT. Synthetic CEDM is able to provide lesion contrast-enhancement level comparable to CEDM.

KW - Contrast Enhanced Digital Breast Tomosynthesis

KW - Contrast Enhanced Digital Mammography

KW - Synthetic contrast enhanced digital mammography

UR - https://www.scopus.com/pages/publications/85050243232

U2 - 10.1117/12.2316371

DO - 10.1117/12.2316371

M3 - Conference contribution

AN - SCOPUS:85050243232

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - 14th International Workshop on Breast Imaging (IWBI 2018)

A2 - Krupinski, Elizabeth A.

PB - SPIE

T2 - 14th International Workshop on Breast Imaging (IWBI 2018)

Y2 - 8 July 2018 through 11 July 2018

ER -

Lesion assessment and radiation dose in contrast-enhanced digital breast tomosynthesis

Abstract

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Conference

Keywords

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