Measurement of the flow induced procoagulant properties of platelets in a mechanical heart valve using prothrombin acetylation

Danny Bluestein; Azhar Siddiqui; Jolyon Jesty

Measurement of the flow induced procoagulant properties of platelets in a mechanical heart valve using prothrombin acetylation

Danny Bluestein
, Azhar Siddiqui
, Jolyon Jesty

Biomedical Engineering

Stony Brook University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

A study was carried out to demonstrate that the acetylated thrombin, in contrast to that produced with normal prothrombin, does not activate human platelets. This allowed to quantify platelet activation by flow stresses only, of a platelet buffer that was recirculated in a flow loop through a St. Jude Medical mechanical heart valve.

Original language	English
Title of host publication	American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Publisher	ASME
Pages	567-568
Number of pages	2
Volume	42
ISBN (Print)	0791816117
State	Published - 1999
Event	1999 Bioengineering Conference - Big Sky, MT, USA Duration: Jun 16 1999 → Jun 20 1999

Conference

Conference	1999 Bioengineering Conference
City	Big Sky, MT, USA
Period	06/16/99 → 06/20/99

Cite this

@inproceedings{d918ed030fc549c7900196e64c163fa0,

title = "Measurement of the flow induced procoagulant properties of platelets in a mechanical heart valve using prothrombin acetylation",

abstract = "A study was carried out to demonstrate that the acetylated thrombin, in contrast to that produced with normal prothrombin, does not activate human platelets. This allowed to quantify platelet activation by flow stresses only, of a platelet buffer that was recirculated in a flow loop through a St. Jude Medical mechanical heart valve.",

author = "Danny Bluestein and Azhar Siddiqui and Jolyon Jesty",

year = "1999",

language = "English",

isbn = "0791816117",

volume = "42",

pages = "567--568",

booktitle = "American Society of Mechanical Engineers, Bioengineering Division (Publication) BED",

publisher = "ASME",

note = "1999 Bioengineering Conference ; Conference date: 16-06-1999 Through 20-06-1999",

}

Measurement of the flow induced procoagulant properties of platelets in a mechanical heart valve using prothrombin acetylation. / Bluestein, Danny; Siddiqui, Azhar; Jesty, Jolyon.
American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol. 42 ASME, 1999. p. 567-568.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Measurement of the flow induced procoagulant properties of platelets in a mechanical heart valve using prothrombin acetylation

AU - Bluestein, Danny

AU - Siddiqui, Azhar

AU - Jesty, Jolyon

PY - 1999

Y1 - 1999

N2 - A study was carried out to demonstrate that the acetylated thrombin, in contrast to that produced with normal prothrombin, does not activate human platelets. This allowed to quantify platelet activation by flow stresses only, of a platelet buffer that was recirculated in a flow loop through a St. Jude Medical mechanical heart valve.

AB - A study was carried out to demonstrate that the acetylated thrombin, in contrast to that produced with normal prothrombin, does not activate human platelets. This allowed to quantify platelet activation by flow stresses only, of a platelet buffer that was recirculated in a flow loop through a St. Jude Medical mechanical heart valve.

UR - https://www.scopus.com/pages/publications/0033297334

M3 - Conference contribution

AN - SCOPUS:0033297334

SN - 0791816117

VL - 42

SP - 567

EP - 568

BT - American Society of Mechanical Engineers, Bioengineering Division (Publication) BED

PB - ASME

T2 - 1999 Bioengineering Conference

Y2 - 16 June 1999 through 20 June 1999

ER -

Measurement of the flow induced procoagulant properties of platelets in a mechanical heart valve using prothrombin acetylation

Abstract

Conference

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