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Mechanobiologic acoustics on bone cellular and in vivo adaptation

  • Stony Brook University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

It is well documented that ultrasound, as a mechanical signal, can produce a wide variety of biological effects in vitro and in vivo. The purpose of the current study was to evaluate acoustics on both in vivo and in vitro adaptation of bone cells and tissue. The results indicated that focused ultrasound can create local fluid flow nearby cells. In vivo results suggest that low-intensity pulse ultrasound can induced mechanical wave in tissue and initiate bone adaptation. Thus, dynamic ultrasound can inhibit bone loss and preserve bone strength under conditions of estrogen deficient osteopenia.

Original languageEnglish
Title of host publication2011 IEEE International Ultrasonics Symposium, IUS 2011
Pages923-926
Number of pages4
DOIs
StatePublished - 2011
Event2011 IEEE International Ultrasonics Symposium, IUS 2011 - Orlando, FL, United States
Duration: Oct 18 2011Oct 21 2011

Publication series

NameIEEE International Ultrasonics Symposium, IUS
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Conference

Conference2011 IEEE International Ultrasonics Symposium, IUS 2011
Country/TerritoryUnited States
CityOrlando, FL
Period10/18/1110/21/11

Keywords

  • acoustic radiation force
  • bone remodeling
  • LIPUS
  • osteopenia

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