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Mechanoreceptors Found in a Posterior Cruciate Ligament From a Well-Functioning Total Knee Arthroplasty Retrieval

  • William M. Mihalko
  • , Aaron T. Creek
  • , Michelle N. Mary
  • , John L. Williams
  • , David E. Komatsu
  • InMotion Orthopaedic Research Center
  • Campbell Clinic Orthopaedics
  • University of Tennessee Health Science Center
  • University of Memphis

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Histologic analysis of the posterior cruciate ligament has been reported in the normal and osteoarthritic knee but not after cruciate-retaining (CR) total knee arthroplasty (TKA). Retention of the posterior cruciate ligament during TKA has been debated as to whether it is beneficial in stability and function. If the presence of mechanoreceptors is shown to be maintained in CR TKA, then there may be an argument for retention. This case report used a retrieval of a well-functioning TKA specimen that had a CR TKA. To prove the presence of mechanoreceptors within the ligament, immunohistochemistry techniques using S100 protein and neurofilament protein were used. This specimen had pacini and lamellar type of mechanoreceptors present on immunohistochemistry analysis. The presence or retention of mechanoreceptors and innervations of the ligament may indicate an advantage when retained during TKA.

Original languageEnglish
Pages (from-to)504.e9-504.e12
JournalJournal of Arthroplasty
Volume26
Issue number3
DOIs
StatePublished - Apr 2011

Keywords

  • Histology
  • Immunohistochemistry
  • Mechanoreceptor
  • Posterior cruciate ligament
  • Total knee arthroplasty

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