Metabolic PET imaging in oncology

Kiran Kumar Solingapuram Sai; Zuzana Zachar; Paul M. Bingham; Akiva Mintz

doi:10.2214/AJR.17.18112

Metabolic PET imaging in oncology

Kiran Kumar Solingapuram Sai
, Zuzana Zachar
, Paul M. Bingham
, Akiva Mintz

Biochemistry and Cell Biology

Wake Forest University
Stony Brook University

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

OBJECTIVE. In this article, we provide a general overview of how cancer cells subvert critical metabolic pathways to support their growth and unchecked division. Furthermore, we outline how molecular imaging can diagnostically exploit the resulting differences between cancer and normal cells. CONCLUSION. Molecular PET can provide valuable information about the metabolic dysregulation in cancer.

Original language	English
Pages (from-to)	270-276
Number of pages	7
Journal	American Journal of Roentgenology
Volume	209
Issue number	2
DOIs	https://doi.org/10.2214/AJR.17.18112
State	Published - Aug 2017

Keywords

FDG
Glutamine
Metabolism
Molecular imaging
PET

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10.2214/AJR.17.18112

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title = "Metabolic PET imaging in oncology",

abstract = "OBJECTIVE. In this article, we provide a general overview of how cancer cells subvert critical metabolic pathways to support their growth and unchecked division. Furthermore, we outline how molecular imaging can diagnostically exploit the resulting differences between cancer and normal cells. CONCLUSION. Molecular PET can provide valuable information about the metabolic dysregulation in cancer.",

keywords = "FDG, Glutamine, Metabolism, Molecular imaging, PET",

author = "Sai, \{Kiran Kumar Solingapuram\} and Zuzana Zachar and Bingham, \{Paul M.\} and Akiva Mintz",

note = "Publisher Copyright: {\textcopyright} American Roentgen Ray Society.",

year = "2017",

month = aug,

doi = "10.2214/AJR.17.18112",

language = "English",

volume = "209",

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AU - Sai, Kiran Kumar Solingapuram

AU - Zachar, Zuzana

AU - Bingham, Paul M.

AU - Mintz, Akiva

N1 - Publisher Copyright: © American Roentgen Ray Society.

PY - 2017/8

Y1 - 2017/8

N2 - OBJECTIVE. In this article, we provide a general overview of how cancer cells subvert critical metabolic pathways to support their growth and unchecked division. Furthermore, we outline how molecular imaging can diagnostically exploit the resulting differences between cancer and normal cells. CONCLUSION. Molecular PET can provide valuable information about the metabolic dysregulation in cancer.

AB - OBJECTIVE. In this article, we provide a general overview of how cancer cells subvert critical metabolic pathways to support their growth and unchecked division. Furthermore, we outline how molecular imaging can diagnostically exploit the resulting differences between cancer and normal cells. CONCLUSION. Molecular PET can provide valuable information about the metabolic dysregulation in cancer.

KW - FDG

KW - Glutamine

KW - Metabolism

KW - Molecular imaging

KW - PET

UR - https://www.scopus.com/pages/publications/85025822171

U2 - 10.2214/AJR.17.18112

DO - 10.2214/AJR.17.18112

M3 - Article

C2 - 28463521

AN - SCOPUS:85025822171

SN - 0361-803X

VL - 209

SP - 270

EP - 276

JO - American Journal of Roentgenology

JF - American Journal of Roentgenology

IS - 2

ER -

Metabolic PET imaging in oncology

Abstract

Keywords

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