Microvillus inclusion disease associated with coarctation of the aorta and bicuspid aortic valve

Grace N. Gathungu; Dinesh S. Pashankar; Carmen D. Sarita-Reyes; Eduardo Zambrano; Miguel Reyes-Mugica; Martina Brueckner; Pramod K. Mistry; Sohail Z. Husain

doi:10.1097/01.mcg.0000225632.07039.b6

Microvillus inclusion disease associated with coarctation of the aorta and bicuspid aortic valve

Grace N. Gathungu
, Dinesh S. Pashankar
, Carmen D. Sarita-Reyes
, Eduardo Zambrano
, Miguel Reyes-Mugica
, Martina Brueckner
, Pramod K. Mistry
, Sohail Z. Husain

Pediatrics

Yale University

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Microvillus inclusion disease is a life-threatening diarrheal disorder of infancy characterized by the presence of microvillus inclusions within the intestinal epithelium. We report a case of a neonate with microvillus inclusion disease that was associated with coarctation of the aorta and bicuspid aortic valve, cardiac malformations within the spectrum of left ventricular outlet tract obstruction. Possible links between the intestinal and cardiac phenotypes are discussed.

Original language	English
Pages (from-to)	400-403
Number of pages	4
Journal	Journal of Clinical Gastroenterology
Volume	42
Issue number	4
DOIs	https://doi.org/10.1097/01.mcg.0000225632.07039.b6
State	Published - Apr 2008

Keywords

Bicuspid aorta
Coarctation
Diarrhea
Left ventricular outflow tract obstruction
Microvillus inclusion disease
NOTCH

Access to Document

10.1097/01.mcg.0000225632.07039.b6

Cite this

@article{a069d4df3ea342e484d3d97de2c71617,

title = "Microvillus inclusion disease associated with coarctation of the aorta and bicuspid aortic valve",

abstract = "Microvillus inclusion disease is a life-threatening diarrheal disorder of infancy characterized by the presence of microvillus inclusions within the intestinal epithelium. We report a case of a neonate with microvillus inclusion disease that was associated with coarctation of the aorta and bicuspid aortic valve, cardiac malformations within the spectrum of left ventricular outlet tract obstruction. Possible links between the intestinal and cardiac phenotypes are discussed.",

keywords = "Bicuspid aorta, Coarctation, Diarrhea, Left ventricular outflow tract obstruction, Microvillus inclusion disease, NOTCH",

author = "Gathungu, \{Grace N.\} and Pashankar, \{Dinesh S.\} and Sarita-Reyes, \{Carmen D.\} and Eduardo Zambrano and Miguel Reyes-Mugica and Martina Brueckner and Mistry, \{Pramod K.\} and Husain, \{Sohail Z.\}",

year = "2008",

month = apr,

doi = "10.1097/01.mcg.0000225632.07039.b6",

language = "English",

volume = "42",

pages = "400--403",

journal = "Journal of Clinical Gastroenterology",

issn = "0192-0790",

number = "4",

}

TY - JOUR

T1 - Microvillus inclusion disease associated with coarctation of the aorta and bicuspid aortic valve

AU - Gathungu, Grace N.

AU - Pashankar, Dinesh S.

AU - Sarita-Reyes, Carmen D.

AU - Zambrano, Eduardo

AU - Reyes-Mugica, Miguel

AU - Brueckner, Martina

AU - Mistry, Pramod K.

AU - Husain, Sohail Z.

PY - 2008/4

Y1 - 2008/4

N2 - Microvillus inclusion disease is a life-threatening diarrheal disorder of infancy characterized by the presence of microvillus inclusions within the intestinal epithelium. We report a case of a neonate with microvillus inclusion disease that was associated with coarctation of the aorta and bicuspid aortic valve, cardiac malformations within the spectrum of left ventricular outlet tract obstruction. Possible links between the intestinal and cardiac phenotypes are discussed.

AB - Microvillus inclusion disease is a life-threatening diarrheal disorder of infancy characterized by the presence of microvillus inclusions within the intestinal epithelium. We report a case of a neonate with microvillus inclusion disease that was associated with coarctation of the aorta and bicuspid aortic valve, cardiac malformations within the spectrum of left ventricular outlet tract obstruction. Possible links between the intestinal and cardiac phenotypes are discussed.

KW - Bicuspid aorta

KW - Coarctation

KW - Diarrhea

KW - Left ventricular outflow tract obstruction

KW - Microvillus inclusion disease

KW - NOTCH

UR - https://www.scopus.com/pages/publications/41349104140

U2 - 10.1097/01.mcg.0000225632.07039.b6

DO - 10.1097/01.mcg.0000225632.07039.b6

M3 - Article

C2 - 18277898

AN - SCOPUS:41349104140

SN - 0192-0790

VL - 42

SP - 400

EP - 403

JO - Journal of Clinical Gastroenterology

JF - Journal of Clinical Gastroenterology

IS - 4

ER -

Microvillus inclusion disease associated with coarctation of the aorta and bicuspid aortic valve

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this