TY - JOUR
T1 - Modified Mediterranean diet and survival
T2 - EPIC-elderly prospective cohort study
AU - Trichopoulou, Antonia
AU - Orfanos, Philippos
AU - Norat, Teresa
AU - Bueno-de-Mesquita, Bas
AU - Ocké, Marga C.
AU - Peeters, Petra H.M.
AU - van der Schouw, Yvonne T.
AU - Boeing, Heiner
AU - Hoffmann, Kurt
AU - Boffetta, Paolo
AU - Nagel, Gabriele
AU - Masala, Giovanna
AU - Krogh, Vittorio
AU - Panico, Salvatore
AU - Tumino, Rosario
AU - Vineis, Paolo
AU - Bamia, Christina
AU - Naska, Androniki
AU - Benetou, Vassiliki
AU - Ferrari, Pietro
AU - Slimani, Nadia
AU - Pera, Guillem
AU - Martinez-Garcia, Carmen
AU - Navarro, Carmen
AU - Rodriguez-Barranco, Miguel
AU - Dorronsoro, Miren
AU - Spencer, Elizabeth A.
AU - Key, Timothy J.
AU - Bingham, Sheila
AU - Khaw, Kay Tee
AU - Kesse, Emmanuelle
AU - Clavel-Chapelon, Francoise
AU - Boutron-Ruault, Marie Christine
AU - Berglund, Goran
AU - Wirfalt, Elisabet
AU - Hallmans, Goran
AU - Johansson, Ingegerd
AU - Tjonneland, Anne
AU - Olsen, Anja
AU - Overvad, Kim
AU - Hundborg, Heidi H.
AU - Riboli, Elio
AU - Trichopoulos, Dimitrios
PY - 2005/4/30
Y1 - 2005/4/30
N2 - Objective: To examine whether adherence to the modified Mediterranean diet, in which unsaturates were substituted for monounsaturates, is associated with longer life expectancy among elderly Europeans. Design: Multicentre, prospective cohort study. Setting: Nine European countries (Denmark, France, Germany, Greece, Italy, the Netherlands, Spain, Sweden, United Kingdom). Participants: 74 607 men and women, aged 60 or more, without coronary heart disease, stroke, or cancer at enrolment and with complete information about dietary intake and potentially confounding variables. Main outcome measures: Extent of adherence to a modified Mediterranean diet using a scoring system on a 10 point scale, and death from any cause by time of occurrence, modelled through Cox regression. Results: An increase in the modified Mediterranean diet score was associated with lower overall mortality, a two unit increment corresponding to a statistically significant reduction of 8% (95% confidence interval 3% to 12%). No statistically significant evidence of heterogeneity was found among countries in the association of the score with overall mortality even though the association was stronger in Greece and Spain. When dietary exposures were calibrated across countries, the reduction in mortality was 7% (1% to 12%). Conclusion: The Mediterranean diet, modified so as to apply across Europe, was associated with increased survival among older people.
AB - Objective: To examine whether adherence to the modified Mediterranean diet, in which unsaturates were substituted for monounsaturates, is associated with longer life expectancy among elderly Europeans. Design: Multicentre, prospective cohort study. Setting: Nine European countries (Denmark, France, Germany, Greece, Italy, the Netherlands, Spain, Sweden, United Kingdom). Participants: 74 607 men and women, aged 60 or more, without coronary heart disease, stroke, or cancer at enrolment and with complete information about dietary intake and potentially confounding variables. Main outcome measures: Extent of adherence to a modified Mediterranean diet using a scoring system on a 10 point scale, and death from any cause by time of occurrence, modelled through Cox regression. Results: An increase in the modified Mediterranean diet score was associated with lower overall mortality, a two unit increment corresponding to a statistically significant reduction of 8% (95% confidence interval 3% to 12%). No statistically significant evidence of heterogeneity was found among countries in the association of the score with overall mortality even though the association was stronger in Greece and Spain. When dietary exposures were calibrated across countries, the reduction in mortality was 7% (1% to 12%). Conclusion: The Mediterranean diet, modified so as to apply across Europe, was associated with increased survival among older people.
UR - https://www.scopus.com/pages/publications/18044368276
U2 - 10.1136/bmj.38415.644155.8F
DO - 10.1136/bmj.38415.644155.8F
M3 - Article
C2 - 15820966
AN - SCOPUS:18044368276
SN - 1756-1833
VL - 330
SP - 991
EP - 995
JO - BMJ (Clinical research ed.)
JF - BMJ (Clinical research ed.)
IS - 7498
ER -