Molecular and phenotypic characterization of methicillin-resistant Staphylococcus aureus isolates causing bacteremia at a major hospital in southern Mississippi

Dhritiman Samanta; Justin L. Batte; Stephanie N. Brown; Angela G. Crosby; Luis A. Marcos; Mohamed O. Elasri

doi:10.1016/j.ajic.2015.01.023

Molecular and phenotypic characterization of methicillin-resistant Staphylococcus aureus isolates causing bacteremia at a major hospital in southern Mississippi

Dhritiman Samanta
, Justin L. Batte
, Stephanie N. Brown
, Angela G. Crosby
, Luis A. Marcos
, Mohamed O. Elasri

Infectious Diseases

University of Southern Mississippi
Forrest General Hospital
Health Laboratory

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Staphylococcus aureus is the predominant cause of bacteremia worldwide. We assessed the molecular epidemiology and antibiotic resistance of methicillin-resistant S aureus isolates causing bacteremia in southern Mississippi. Diverse genetic backgrounds in terms of staphylococcal cassette chromosome mec, pulsed-field gel electrophoresis, and multilocus sequence typing types of methicillin-resistant S aureus were identified as causing bacteremia in Mississippi. A strong association of Panton-Valentine leukocidin genes with elevated vancomycin minimum inhibitory concentration is one of the important findings of our study.

Original language	English
Pages (from-to)	540-542
Number of pages	3
Journal	American Journal of Infection Control
Volume	43
Issue number	5
DOIs	https://doi.org/10.1016/j.ajic.2015.01.023
State	Published - May 1 2015

Keywords

Epidemiology
PVL
Vancomycin

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10.1016/j.ajic.2015.01.023

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title = "Molecular and phenotypic characterization of methicillin-resistant Staphylococcus aureus isolates causing bacteremia at a major hospital in southern Mississippi",

abstract = "Staphylococcus aureus is the predominant cause of bacteremia worldwide. We assessed the molecular epidemiology and antibiotic resistance of methicillin-resistant S aureus isolates causing bacteremia in southern Mississippi. Diverse genetic backgrounds in terms of staphylococcal cassette chromosome mec, pulsed-field gel electrophoresis, and multilocus sequence typing types of methicillin-resistant S aureus were identified as causing bacteremia in Mississippi. A strong association of Panton-Valentine leukocidin genes with elevated vancomycin minimum inhibitory concentration is one of the important findings of our study.",

keywords = "Epidemiology, PVL, Vancomycin",

author = "Dhritiman Samanta and Batte, \{Justin L.\} and Brown, \{Stephanie N.\} and Crosby, \{Angela G.\} and Marcos, \{Luis A.\} and Elasri, \{Mohamed O.\}",

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doi = "10.1016/j.ajic.2015.01.023",

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journal = "American Journal of Infection Control",

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Molecular and phenotypic characterization of methicillin-resistant Staphylococcus aureus isolates causing bacteremia at a major hospital in southern Mississippi. / Samanta, Dhritiman; Batte, Justin L.; Brown, Stephanie N. et al.
In: American Journal of Infection Control, Vol. 43, No. 5, 01.05.2015, p. 540-542.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Molecular and phenotypic characterization of methicillin-resistant Staphylococcus aureus isolates causing bacteremia at a major hospital in southern Mississippi

AU - Samanta, Dhritiman

AU - Batte, Justin L.

AU - Brown, Stephanie N.

AU - Crosby, Angela G.

AU - Marcos, Luis A.

AU - Elasri, Mohamed O.

PY - 2015/5/1

Y1 - 2015/5/1

N2 - Staphylococcus aureus is the predominant cause of bacteremia worldwide. We assessed the molecular epidemiology and antibiotic resistance of methicillin-resistant S aureus isolates causing bacteremia in southern Mississippi. Diverse genetic backgrounds in terms of staphylococcal cassette chromosome mec, pulsed-field gel electrophoresis, and multilocus sequence typing types of methicillin-resistant S aureus were identified as causing bacteremia in Mississippi. A strong association of Panton-Valentine leukocidin genes with elevated vancomycin minimum inhibitory concentration is one of the important findings of our study.

AB - Staphylococcus aureus is the predominant cause of bacteremia worldwide. We assessed the molecular epidemiology and antibiotic resistance of methicillin-resistant S aureus isolates causing bacteremia in southern Mississippi. Diverse genetic backgrounds in terms of staphylococcal cassette chromosome mec, pulsed-field gel electrophoresis, and multilocus sequence typing types of methicillin-resistant S aureus were identified as causing bacteremia in Mississippi. A strong association of Panton-Valentine leukocidin genes with elevated vancomycin minimum inhibitory concentration is one of the important findings of our study.

KW - Epidemiology

KW - PVL

KW - Vancomycin

UR - https://www.scopus.com/pages/publications/84929519762

U2 - 10.1016/j.ajic.2015.01.023

DO - 10.1016/j.ajic.2015.01.023

M3 - Article

C2 - 25737304

AN - SCOPUS:84929519762

SN - 0196-6553

VL - 43

SP - 540

EP - 542

JO - American Journal of Infection Control

JF - American Journal of Infection Control

IS - 5

ER -

Molecular and phenotypic characterization of methicillin-resistant Staphylococcus aureus isolates causing bacteremia at a major hospital in southern Mississippi

Abstract

Keywords

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