Molecular conformations of DNA targets captured by model nanoarrays

X. Hao; E. A. Josephs; Q. Gu; T. Ye

doi:10.1039/c7nr04715k

Molecular conformations of DNA targets captured by model nanoarrays

X. Hao
, E. A. Josephs
, Q. Gu
, T. Ye

Biomedical Engineering

University of California Merced

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

An open question in single molecule nanoarrays is how the chemical and morphological heterogeneities of the solid support affect the properties of biomacromolecules. We generated arrays that allowed individually-resolvable DNA molecules to interact with tailored surface heterogeneities and revealed how molecular conformations are impacted by surface interactions.

Original language	English
Pages (from-to)	13419-13424
Number of pages	6
Journal	Nanoscale
Volume	9
Issue number	36
DOIs	https://doi.org/10.1039/c7nr04715k
State	Published - Sep 28 2017

Access to Document

10.1039/c7nr04715k

Cite this

@article{46f5aa7c9ffd40b49cd8270c1ecc9e3d,

title = "Molecular conformations of DNA targets captured by model nanoarrays",

abstract = "An open question in single molecule nanoarrays is how the chemical and morphological heterogeneities of the solid support affect the properties of biomacromolecules. We generated arrays that allowed individually-resolvable DNA molecules to interact with tailored surface heterogeneities and revealed how molecular conformations are impacted by surface interactions.",

author = "X. Hao and Josephs, \{E. A.\} and Q. Gu and T. Ye",

note = "Publisher Copyright: {\textcopyright} 2017 The Royal Society of Chemistry.",

year = "2017",

month = sep,

day = "28",

doi = "10.1039/c7nr04715k",

language = "English",

volume = "9",

pages = "13419--13424",

journal = "Nanoscale",

issn = "2040-3364",

number = "36",

}

TY - JOUR

T1 - Molecular conformations of DNA targets captured by model nanoarrays

AU - Hao, X.

AU - Josephs, E. A.

AU - Gu, Q.

AU - Ye, T.

PY - 2017/9/28

Y1 - 2017/9/28

N2 - An open question in single molecule nanoarrays is how the chemical and morphological heterogeneities of the solid support affect the properties of biomacromolecules. We generated arrays that allowed individually-resolvable DNA molecules to interact with tailored surface heterogeneities and revealed how molecular conformations are impacted by surface interactions.

AB - An open question in single molecule nanoarrays is how the chemical and morphological heterogeneities of the solid support affect the properties of biomacromolecules. We generated arrays that allowed individually-resolvable DNA molecules to interact with tailored surface heterogeneities and revealed how molecular conformations are impacted by surface interactions.

UR - https://www.scopus.com/pages/publications/85029890753

U2 - 10.1039/c7nr04715k

DO - 10.1039/c7nr04715k

M3 - Article

C2 - 28875997

AN - SCOPUS:85029890753

SN - 2040-3364

VL - 9

SP - 13419

EP - 13424

JO - Nanoscale

JF - Nanoscale

IS - 36

ER -

Molecular conformations of DNA targets captured by model nanoarrays

Abstract

Access to Document

Other files and links

Fingerprint

Cite this