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Monoclonal antibodies specific for v-abl- and c-abl-encoded molecules

  • L. Schiff-Maker
  • , M. C. Burns
  • , J. B. Konopka
  • , S. Clark
  • , O. N. Witte
  • , N. Rosenberg
  • Tufts University

Research output: Contribution to journalArticlepeer-review

52 Scopus citations

Abstract

Monoclonal antibodies specific for regions of the transforming protein of Abelson murine leukemia virus were prepared. Antibodies directed against the kinase domain inhibited the autophosphorylation of v-abl proteins, and all of the antibodies reacted with the products of the murine and human c-abl loci.

Original languageEnglish
Pages (from-to)1182-1186
Number of pages5
JournalJournal of Virology
Volume57
Issue number3
DOIs
StatePublished - 1986

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