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Multicenter clinical evaluation of the Du Pont HERPCHEK(TM) HSV ELISA, a new rapid diagnostic test for the direct detection of herpes simplex virus

  • D. A. Baker
  • , D. Pavan-Langston
  • , B. Gonik
  • , P. O. Milch
  • , E. C. Dunkel
  • , A. Berkowitz
  • , M. B. Woodin
  • , A. Philip
  • , R. J. Vander-Mallie
  • , M. N. Bobrow
  • , G. Cukor
  • Stony Brook University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

7 Scopus citations

Abstract

A new 4h rapid enzyme-immunoassay for direct detection of herpes simplex virus (HSV) antigen (Du Pont HERPCHEK(TM)) was evaluated with 743 clinical samples collected at obstetrics and gynecology (OB/GYN), sexually transmitted diseases (STD), and ophthalmology clinics. The sensitivity and specificity of HERPCHEK(TM) was 98.0% and 98.4% respectively compared to virus isolation in cell culture. Confirmatory blocking ELISA tests, clinical history and follow up indicate that the true specificity of the test is 100%.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
Pages71-76
Number of pages6
DOIs
StatePublished - 1989

Publication series

NameAdvances in Experimental Medicine and Biology
Volume263

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