Negative autoregulation by the Escherichia coli SoxS protein: A dampening mechanism for the soxRS redox stress response

T. Nunoshiba; E. Hidalgo; Z. Li; B. Demple

doi:10.1128/jb.175.22.7492-7494.1993

Negative autoregulation by the Escherichia coli SoxS protein: A dampening mechanism for the soxRS redox stress response

T. Nunoshiba
, E. Hidalgo
, Z. Li
, B. Demple

Pharmacological Sciences

Harvard University

Research output: Contribution to journal › Comment/debate

55 Scopus citations

Abstract

The soxRS redox stress regulon of Escherichia coli is triggered in two stages, with the activated SoxR protein stimulating the soxS gene, whose product then triggers transcription of ~10 promoters. Genetic and biochemical experiments presented here show that SoxS protein also limits soxS transcription in vivo and binds the soxS promoter in vitro.

Original language	English
Pages (from-to)	7492-7494
Number of pages	3
Journal	Journal of Bacteriology
Volume	175
Issue number	22
DOIs	https://doi.org/10.1128/jb.175.22.7492-7494.1993
State	Published - 1993

Access to Document

10.1128/jb.175.22.7492-7494.1993

Cite this

@article{f1ddb2245c7b4083af55441126239165,

title = "Negative autoregulation by the Escherichia coli SoxS protein: A dampening mechanism for the soxRS redox stress response",

abstract = "The soxRS redox stress regulon of Escherichia coli is triggered in two stages, with the activated SoxR protein stimulating the soxS gene, whose product then triggers transcription of \textasciitilde{}10 promoters. Genetic and biochemical experiments presented here show that SoxS protein also limits soxS transcription in vivo and binds the soxS promoter in vitro.",

author = "T. Nunoshiba and E. Hidalgo and Z. Li and B. Demple",

year = "1993",

doi = "10.1128/jb.175.22.7492-7494.1993",

language = "English",

volume = "175",

pages = "7492--7494",

journal = "Journal of Bacteriology",

issn = "0021-9193",

number = "22",

}

TY - JOUR

T1 - Negative autoregulation by the Escherichia coli SoxS protein

T2 - A dampening mechanism for the soxRS redox stress response

AU - Nunoshiba, T.

AU - Hidalgo, E.

AU - Li, Z.

AU - Demple, B.

PY - 1993

Y1 - 1993

N2 - The soxRS redox stress regulon of Escherichia coli is triggered in two stages, with the activated SoxR protein stimulating the soxS gene, whose product then triggers transcription of ~10 promoters. Genetic and biochemical experiments presented here show that SoxS protein also limits soxS transcription in vivo and binds the soxS promoter in vitro.

AB - The soxRS redox stress regulon of Escherichia coli is triggered in two stages, with the activated SoxR protein stimulating the soxS gene, whose product then triggers transcription of ~10 promoters. Genetic and biochemical experiments presented here show that SoxS protein also limits soxS transcription in vivo and binds the soxS promoter in vitro.

UR - https://www.scopus.com/pages/publications/0027432048

U2 - 10.1128/jb.175.22.7492-7494.1993

DO - 10.1128/jb.175.22.7492-7494.1993

M3 - Comment/debate

C2 - 8226698

AN - SCOPUS:0027432048

SN - 0021-9193

VL - 175

SP - 7492

EP - 7494

JO - Journal of Bacteriology

JF - Journal of Bacteriology

IS - 22

ER -

Negative autoregulation by the Escherichia coli SoxS protein: A dampening mechanism for the soxRS redox stress response

Abstract

Access to Document

Other files and links

Fingerprint

Cite this