New approaches to the asymmetric synthesis of dipeptide isosteres via β-Lactam Synthon Method

Iwao Ojima; Hong Wang; Tao Wang; Edward W. Ng

doi:10.1016/S0040-4039(97)10677-3

New approaches to the asymmetric synthesis of dipeptide isosteres via β-Lactam Synthon Method

Iwao Ojima
, Hong Wang
, Tao Wang
, Edward W. Ng

Chemistry

Stony Brook University

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

New and efficient synthetic routes to dipeptide isosteres with high enantiomeric purity, e.g., hydroxyethylene, dihydroxyethylene and hydroxyethylamine isosteres, have been developed via oxiranes 6 and formyloxazolines 13 derived from N-t-Boc-β-lactams 4.

Original language	English
Pages (from-to)	923-926
Number of pages	4
Journal	Tetrahedron Letters
Volume	39
Issue number	9
DOIs	https://doi.org/10.1016/S0040-4039(97)10677-3
State	Published - Feb 26 1998

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@article{2d5dc049bf18415995ed35e6950dd6c7,

title = "New approaches to the asymmetric synthesis of dipeptide isosteres via β-Lactam Synthon Method",

abstract = "New and efficient synthetic routes to dipeptide isosteres with high enantiomeric purity, e.g., hydroxyethylene, dihydroxyethylene and hydroxyethylamine isosteres, have been developed via oxiranes 6 and formyloxazolines 13 derived from N-t-Boc-β-lactams 4.",

author = "Iwao Ojima and Hong Wang and Tao Wang and Ng, \{Edward W.\}",

year = "1998",

month = feb,

day = "26",

doi = "10.1016/S0040-4039(97)10677-3",

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TY - JOUR

T1 - New approaches to the asymmetric synthesis of dipeptide isosteres via β-Lactam Synthon Method

AU - Ojima, Iwao

AU - Wang, Hong

AU - Wang, Tao

AU - Ng, Edward W.

PY - 1998/2/26

Y1 - 1998/2/26

N2 - New and efficient synthetic routes to dipeptide isosteres with high enantiomeric purity, e.g., hydroxyethylene, dihydroxyethylene and hydroxyethylamine isosteres, have been developed via oxiranes 6 and formyloxazolines 13 derived from N-t-Boc-β-lactams 4.

AB - New and efficient synthetic routes to dipeptide isosteres with high enantiomeric purity, e.g., hydroxyethylene, dihydroxyethylene and hydroxyethylamine isosteres, have been developed via oxiranes 6 and formyloxazolines 13 derived from N-t-Boc-β-lactams 4.

UR - https://www.scopus.com/pages/publications/0032567898

U2 - 10.1016/S0040-4039(97)10677-3

DO - 10.1016/S0040-4039(97)10677-3

M3 - Article

AN - SCOPUS:0032567898

SN - 0040-4039

VL - 39

SP - 923

EP - 926

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 9

ER -

New approaches to the asymmetric synthesis of dipeptide isosteres via β-Lactam Synthon Method

Abstract

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