NIRS-based quantitative measurement of autoregulatory effects on microvascular hemoglobin oxygenation: Assessment of differences between non-diabetic and type II diabetic subjects

Onyeoziri R. Nwanguma; Harry L. Graber; Rahul Valluru; Randall L. Barbour

doi:10.1364/biomed.2008.bsue57

NIRS-based quantitative measurement of autoregulatory effects on microvascular hemoglobin oxygenation: Assessment of differences between non-diabetic and type II diabetic subjects

Onyeoziri R. Nwanguma
, Harry L. Graber
, Rahul Valluru
, Randall L. Barbour

Geriatric and General Medicine

SUNY Downstate Health Sciences University
NIRx Medical Technologies LLC

Research output: Contribution to conference › Paper › peer-review

Abstract

By examining the simultaneous evolution of oxyhemoglobin and deoxyhemoglobin in NIRS image time series, we have derived indices of the competency of autoregulation. Applying these measures to data collected from the forearms of type II diabetics and normal subjects reveals statistically significant differences between the two patient populations. While some of the analyses involve application of a transient ischemia protocol, others consider only resting baseline data.

Original language	English
Pages	BSuE57
DOIs	https://doi.org/10.1364/biomed.2008.bsue57
State	Published - 2008
Event	Biomedical Optics, BIOMED 2008 - St. Petersburg, FL, United States Duration: Mar 16 2008 → Mar 19 2008

Conference

Conference	Biomedical Optics, BIOMED 2008
Country/Territory	United States
City	St. Petersburg, FL
Period	03/16/08 → 03/19/08

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10.1364/biomed.2008.bsue57

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Nwanguma, O. R., Graber, H. L., Valluru, R., & Barbour, R. L. (2008). NIRS-based quantitative measurement of autoregulatory effects on microvascular hemoglobin oxygenation: Assessment of differences between non-diabetic and type II diabetic subjects. BSuE57. Paper presented at Biomedical Optics, BIOMED 2008, St. Petersburg, FL, United States. https://doi.org/10.1364/biomed.2008.bsue57

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title = "NIRS-based quantitative measurement of autoregulatory effects on microvascular hemoglobin oxygenation: Assessment of differences between non-diabetic and type II diabetic subjects",

abstract = "By examining the simultaneous evolution of oxyhemoglobin and deoxyhemoglobin in NIRS image time series, we have derived indices of the competency of autoregulation. Applying these measures to data collected from the forearms of type II diabetics and normal subjects reveals statistically significant differences between the two patient populations. While some of the analyses involve application of a transient ischemia protocol, others consider only resting baseline data.",

author = "Nwanguma, \{Onyeoziri R.\} and Graber, \{Harry L.\} and Rahul Valluru and Barbour, \{Randall L.\}",

year = "2008",

doi = "10.1364/biomed.2008.bsue57",

language = "English",

pages = "BSuE57",

note = "Biomedical Optics, BIOMED 2008 ; Conference date: 16-03-2008 Through 19-03-2008",

}

Nwanguma, OR, Graber, HL, Valluru, R & Barbour, RL 2008, 'NIRS-based quantitative measurement of autoregulatory effects on microvascular hemoglobin oxygenation: Assessment of differences between non-diabetic and type II diabetic subjects', Paper presented at Biomedical Optics, BIOMED 2008, St. Petersburg, FL, United States, 03/16/08 - 03/19/08 pp. BSuE57. https://doi.org/10.1364/biomed.2008.bsue57

NIRS-based quantitative measurement of autoregulatory effects on microvascular hemoglobin oxygenation: Assessment of differences between non-diabetic and type II diabetic subjects. / Nwanguma, Onyeoziri R.; Graber, Harry L.; Valluru, Rahul et al.
2008. BSuE57 Paper presented at Biomedical Optics, BIOMED 2008, St. Petersburg, FL, United States.

Research output: Contribution to conference › Paper › peer-review

TY - CONF

T1 - NIRS-based quantitative measurement of autoregulatory effects on microvascular hemoglobin oxygenation

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AU - Nwanguma, Onyeoziri R.

AU - Graber, Harry L.

AU - Valluru, Rahul

AU - Barbour, Randall L.

PY - 2008

Y1 - 2008

N2 - By examining the simultaneous evolution of oxyhemoglobin and deoxyhemoglobin in NIRS image time series, we have derived indices of the competency of autoregulation. Applying these measures to data collected from the forearms of type II diabetics and normal subjects reveals statistically significant differences between the two patient populations. While some of the analyses involve application of a transient ischemia protocol, others consider only resting baseline data.

AB - By examining the simultaneous evolution of oxyhemoglobin and deoxyhemoglobin in NIRS image time series, we have derived indices of the competency of autoregulation. Applying these measures to data collected from the forearms of type II diabetics and normal subjects reveals statistically significant differences between the two patient populations. While some of the analyses involve application of a transient ischemia protocol, others consider only resting baseline data.

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DO - 10.1364/biomed.2008.bsue57

M3 - Paper

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SP - BSuE57

Y2 - 16 March 2008 through 19 March 2008

ER -

NIRS-based quantitative measurement of autoregulatory effects on microvascular hemoglobin oxygenation: Assessment of differences between non-diabetic and type II diabetic subjects

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