Non-Invasive Continuous Monitoring of Cerebral Blood Flow after Traumatic Brain Injury in Mice Using Fiber Camera-Based Speckle Contrast Optical Spectroscopy

Dharminder Langri; Ulas Sunar

Non-Invasive Continuous Monitoring of Cerebral Blood Flow after Traumatic Brain Injury in Mice Using Fiber Camera-Based Speckle Contrast Optical Spectroscopy

Dharminder Langri
, Ulas Sunar

Dept of Biomedical Engineering

Wright State University

Research output: Contribution to conference › Paper › peer-review

Abstract

We implemented a laser speckle contrast imaging technique with a fiber camera-based approach to monitor blood flow changes in a mouse model post-closed head injury, revealing a significant (~10%, p < 0.05) decrease within 30 minutes. This suggests the potential of blood flow as an early biomarker for head injuries, highlighting the technique's utility for continuous monitoring and clinical translation.

Original language	English
State	Published - 2024
Event	Microscopy Histopathology and Analytics, Microscopy 2024 - Part of Optica Biophotonics Congress: Biomedical Optics - Fort Lauderdale, United States Duration: Apr 7 2024 → Apr 10 2024

Conference

Conference	Microscopy Histopathology and Analytics, Microscopy 2024 - Part of Optica Biophotonics Congress: Biomedical Optics
Country/Territory	United States
City	Fort Lauderdale
Period	04/7/24 → 04/10/24

Cite this

@conference{ae9eec72ead944f68601d69adf43e5f7,

title = "Non-Invasive Continuous Monitoring of Cerebral Blood Flow after Traumatic Brain Injury in Mice Using Fiber Camera-Based Speckle Contrast Optical Spectroscopy",

abstract = "We implemented a laser speckle contrast imaging technique with a fiber camera-based approach to monitor blood flow changes in a mouse model post-closed head injury, revealing a significant (\textasciitilde{}10\%, p < 0.05) decrease within 30 minutes. This suggests the potential of blood flow as an early biomarker for head injuries, highlighting the technique's utility for continuous monitoring and clinical translation.",

author = "Dharminder Langri and Ulas Sunar",

note = "Publisher Copyright: {\textcopyright} 2024 The Author(s); Microscopy Histopathology and Analytics, Microscopy 2024 - Part of Optica Biophotonics Congress: Biomedical Optics ; Conference date: 07-04-2024 Through 10-04-2024",

year = "2024",

language = "English",

}

Langri, D & Sunar, U 2024, 'Non-Invasive Continuous Monitoring of Cerebral Blood Flow after Traumatic Brain Injury in Mice Using Fiber Camera-Based Speckle Contrast Optical Spectroscopy', Paper presented at Microscopy Histopathology and Analytics, Microscopy 2024 - Part of Optica Biophotonics Congress: Biomedical Optics, Fort Lauderdale, United States, 04/7/24 - 04/10/24.

Non-Invasive Continuous Monitoring of Cerebral Blood Flow after Traumatic Brain Injury in Mice Using Fiber Camera-Based Speckle Contrast Optical Spectroscopy. / Langri, Dharminder; Sunar, Ulas.
2024. Paper presented at Microscopy Histopathology and Analytics, Microscopy 2024 - Part of Optica Biophotonics Congress: Biomedical Optics, Fort Lauderdale, United States.

Research output: Contribution to conference › Paper › peer-review

TY - CONF

T1 - Non-Invasive Continuous Monitoring of Cerebral Blood Flow after Traumatic Brain Injury in Mice Using Fiber Camera-Based Speckle Contrast Optical Spectroscopy

AU - Langri, Dharminder

AU - Sunar, Ulas

PY - 2024

Y1 - 2024

N2 - We implemented a laser speckle contrast imaging technique with a fiber camera-based approach to monitor blood flow changes in a mouse model post-closed head injury, revealing a significant (~10%, p < 0.05) decrease within 30 minutes. This suggests the potential of blood flow as an early biomarker for head injuries, highlighting the technique's utility for continuous monitoring and clinical translation.

AB - We implemented a laser speckle contrast imaging technique with a fiber camera-based approach to monitor blood flow changes in a mouse model post-closed head injury, revealing a significant (~10%, p < 0.05) decrease within 30 minutes. This suggests the potential of blood flow as an early biomarker for head injuries, highlighting the technique's utility for continuous monitoring and clinical translation.

UR - https://www.scopus.com/pages/publications/85204881572

M3 - Paper

AN - SCOPUS:85204881572

T2 - Microscopy Histopathology and Analytics, Microscopy 2024 - Part of Optica Biophotonics Congress: Biomedical Optics

Y2 - 7 April 2024 through 10 April 2024

ER -

Non-Invasive Continuous Monitoring of Cerebral Blood Flow after Traumatic Brain Injury in Mice Using Fiber Camera-Based Speckle Contrast Optical Spectroscopy

Abstract

Conference

Other files and links

Fingerprint

Cite this