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Non-Invasive Continuous Monitoring of Cerebral Blood Flow after Traumatic Brain Injury in Mice Using Fiber Camera-Based Speckle Contrast Optical Spectroscopy

  • Wright State University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We implemented a laser speckle contrast imaging technique with a fiber camera-based approach to monitor blood flow changes in a mouse model post-closed head injury, revealing a significant (~10%, p < 0.05) decrease within 30 minutes. This suggests the potential of blood flow as an early biomarker for head injuries, highlighting the technique's utility for continuous monitoring and clinical translation.

Original languageEnglish
Title of host publicationOptics and the Brain, BRAIN 2024 in Proceedings Optica Biophotonics Congress
Subtitle of host publicationBiomedical Optics 2024, Translational, Microscopy, OCT, OTS, BRAIN - Part of Optica Biophotonics Congress: Biomedical Optics
PublisherOptical Society of America
ISBN (Electronic)9781957171340
DOIs
StatePublished - 2024
EventOptics and the Brain, BRAIN 2024 - Part of Optica Biophotonics Congress: Biomedical Optics - Fort Lauderdale, United States
Duration: Apr 7 2024Apr 10 2024

Publication series

NameOptics and the Brain, BRAIN 2024 in Proceedings Optica Biophotonics Congress: Biomedical Optics 2024, Translational, Microscopy, OCT, OTS, BRAIN - Part of Optica Biophotonics Congress: Biomedical Optics

Conference

ConferenceOptics and the Brain, BRAIN 2024 - Part of Optica Biophotonics Congress: Biomedical Optics
Country/TerritoryUnited States
CityFort Lauderdale
Period04/7/2404/10/24

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