Normocalcemic Hyperparathyroidism: Routine Surgery?

Andres Tame-Elorduy; Thomas Szabo Yamashita; Nancy D. Perrier; Michael S. Lui; Theresa A. Guise

doi:10.1007/978-3-031-81813-4_17

Normocalcemic Hyperparathyroidism: Routine Surgery?

Andres Tame-Elorduy
, Thomas Szabo Yamashita
, Nancy D. Perrier
, Michael S. Lui
, Theresa A. Guise

Surgery

University of Texas MD Anderson Cancer Center

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The diagnosis of normocalcemic hyperparathyroidism is made based on biochemical analysis and is characterized by consistently elevated parathyroid hormone levels with normal serum calcium levels. It is important to distinguish this clinical entity from secondary causes of parathyroid hormone elevation. Patients with this condition are often identified during evaluation of osteoporosis or nephrolithiasis and compared to patients with classic primary hyperparathyroidism are more likely to have multigland disease identified at the time of surgery. Surgery may involve targeted parathyroidectomy or bilateral exploration with removal of multiple parathyroid glands. The goal of surgery is normal calcium and parathyroid hormone levels at 6 months postoperatively with improved bone mineral density.

Original language	English
Title of host publication	Medical and Surgical Treatment of Parathyroid Diseases
Subtitle of host publication	An Evidence-Based Approach
Publisher	Springer Science+Business Media
Pages	193-198
Number of pages	6
ISBN (Electronic)	9783031818134
ISBN (Print)	9783031818127
DOIs	https://doi.org/10.1007/978-3-031-81813-4_17
State	Published - Jan 1 2025

Keywords

Bone density
Nephrolithiasis
Normocalcemic hyperparathyroidism
Osteoporosis
Secondary hyperparathyroidism

Access to Document

10.1007/978-3-031-81813-4_17

Cite this

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title = "Normocalcemic Hyperparathyroidism: Routine Surgery?",

abstract = "The diagnosis of normocalcemic hyperparathyroidism is made based on biochemical analysis and is characterized by consistently elevated parathyroid hormone levels with normal serum calcium levels. It is important to distinguish this clinical entity from secondary causes of parathyroid hormone elevation. Patients with this condition are often identified during evaluation of osteoporosis or nephrolithiasis and compared to patients with classic primary hyperparathyroidism are more likely to have multigland disease identified at the time of surgery. Surgery may involve targeted parathyroidectomy or bilateral exploration with removal of multiple parathyroid glands. The goal of surgery is normal calcium and parathyroid hormone levels at 6 months postoperatively with improved bone mineral density.",

keywords = "Bone density, Nephrolithiasis, Normocalcemic hyperparathyroidism, Osteoporosis, Secondary hyperparathyroidism",

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AU - Guise, Theresa A.

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KW - Osteoporosis

KW - Secondary hyperparathyroidism

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ER -

Normocalcemic Hyperparathyroidism: Routine Surgery?

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