One-pot desulfurative-fluorination-bromination. Synthesis of 2,5-dibromo-3-(1,1-difluoroalkyl)thiophenes

Nashaat Turkman; Lingling An; Martin Pomerantz

doi:10.1021/ol101907k

One-pot desulfurative-fluorination-bromination. Synthesis of 2,5-dibromo-3-(1,1-difluoroalkyl)thiophenes

Nashaat Turkman
, Lingling An
, Martin Pomerantz

Radiology

University of Texas at Arlington

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Figure Presented. A unique one-pot, high-yield desulfurative-fluorination- bromination reaction which leads to the synthesis of 2,5-dibromo-3-(1,1- difluoroalkyl)thiophenes is reported. A single dithiolane reactant can be used to produce both 2,5-dibromo-3-(1,1-difluoroalkyl)thiophene and 3-(1,1-difluoroalkyl)thiophene with longer alkyl chains.

Original language	English
Pages (from-to)	4428-4430
Number of pages	3
Journal	Organic Letters
Volume	12
Issue number	19
DOIs	https://doi.org/10.1021/ol101907k
State	Published - Oct 1 2010

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title = "One-pot desulfurative-fluorination-bromination. Synthesis of 2,5-dibromo-3-(1,1-difluoroalkyl)thiophenes",

abstract = "Figure Presented. A unique one-pot, high-yield desulfurative-fluorination- bromination reaction which leads to the synthesis of 2,5-dibromo-3-(1,1- difluoroalkyl)thiophenes is reported. A single dithiolane reactant can be used to produce both 2,5-dibromo-3-(1,1-difluoroalkyl)thiophene and 3-(1,1-difluoroalkyl)thiophene with longer alkyl chains.",

author = "Nashaat Turkman and Lingling An and Martin Pomerantz",

year = "2010",

month = oct,

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doi = "10.1021/ol101907k",

language = "English",

volume = "12",

pages = "4428--4430",

journal = "Organic Letters",

issn = "1523-7060",

number = "19",

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T1 - One-pot desulfurative-fluorination-bromination. Synthesis of 2,5-dibromo-3-(1,1-difluoroalkyl)thiophenes

AU - Turkman, Nashaat

AU - An, Lingling

AU - Pomerantz, Martin

PY - 2010/10/1

Y1 - 2010/10/1

N2 - Figure Presented. A unique one-pot, high-yield desulfurative-fluorination- bromination reaction which leads to the synthesis of 2,5-dibromo-3-(1,1- difluoroalkyl)thiophenes is reported. A single dithiolane reactant can be used to produce both 2,5-dibromo-3-(1,1-difluoroalkyl)thiophene and 3-(1,1-difluoroalkyl)thiophene with longer alkyl chains.

AB - Figure Presented. A unique one-pot, high-yield desulfurative-fluorination- bromination reaction which leads to the synthesis of 2,5-dibromo-3-(1,1- difluoroalkyl)thiophenes is reported. A single dithiolane reactant can be used to produce both 2,5-dibromo-3-(1,1-difluoroalkyl)thiophene and 3-(1,1-difluoroalkyl)thiophene with longer alkyl chains.

UR - https://www.scopus.com/pages/publications/77957140982

U2 - 10.1021/ol101907k

DO - 10.1021/ol101907k

M3 - Article

AN - SCOPUS:77957140982

SN - 1523-7060

VL - 12

SP - 4428

EP - 4430

JO - Organic Letters

JF - Organic Letters

IS - 19

ER -

One-pot desulfurative-fluorination-bromination. Synthesis of 2,5-dibromo-3-(1,1-difluoroalkyl)thiophenes

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