Optical coherence - Gated imaging of biological tissues

Y. Pan; E. Lankenau; J. Welzel; R. Birngruber; R. Engelhardt

doi:10.1109/2944.577332

Optical coherence - Gated imaging of biological tissues

Y. Pan
, E. Lankenau
, J. Welzel
, R. Birngruber
, R. Engelhardt

Biomedical Engineering

Ger
Medizinisches Laserzentrum Lubeck

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

We present optical coherence-gated tomography (OCT) in turbid biological tissues. The fast OCT system that is used in this study is a single-mode fiber-optic interferometer with low-coherence light at 830 nm which can perform a cross-sectional image of 250-600 pixels in a few seconds. Preliminary results suggest that OCT can provide high-resolution imaging in low-scattering and high-scattering superficial tissues. In vitro imaging of porcine cornea after being coagulated with a laser shows that OCT is a promising tool for the evaluation of pathological structures in low-scattering tissue. This technique can also be used to diagnose diseases in high-scattering tissues like bladder and living skin. In addition, 50-MHz ultrasound images and histological pictures are presented for comparison with OCT.

Original language	English
Pages (from-to)	1029-1034
Number of pages	6
Journal	IEEE Journal of Selected Topics in Quantum Electronics
Volume	2
Issue number	4
DOIs	https://doi.org/10.1109/2944.577332
State	Published - Dec 1996

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title = "Optical coherence - Gated imaging of biological tissues",

abstract = "We present optical coherence-gated tomography (OCT) in turbid biological tissues. The fast OCT system that is used in this study is a single-mode fiber-optic interferometer with low-coherence light at 830 nm which can perform a cross-sectional image of 250-600 pixels in a few seconds. Preliminary results suggest that OCT can provide high-resolution imaging in low-scattering and high-scattering superficial tissues. In vitro imaging of porcine cornea after being coagulated with a laser shows that OCT is a promising tool for the evaluation of pathological structures in low-scattering tissue. This technique can also be used to diagnose diseases in high-scattering tissues like bladder and living skin. In addition, 50-MHz ultrasound images and histological pictures are presented for comparison with OCT.",

author = "Y. Pan and E. Lankenau and J. Welzel and R. Birngruber and R. Engelhardt",

year = "1996",

month = dec,

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AU - Lankenau, E.

AU - Welzel, J.

AU - Birngruber, R.

AU - Engelhardt, R.

PY - 1996/12

Y1 - 1996/12

N2 - We present optical coherence-gated tomography (OCT) in turbid biological tissues. The fast OCT system that is used in this study is a single-mode fiber-optic interferometer with low-coherence light at 830 nm which can perform a cross-sectional image of 250-600 pixels in a few seconds. Preliminary results suggest that OCT can provide high-resolution imaging in low-scattering and high-scattering superficial tissues. In vitro imaging of porcine cornea after being coagulated with a laser shows that OCT is a promising tool for the evaluation of pathological structures in low-scattering tissue. This technique can also be used to diagnose diseases in high-scattering tissues like bladder and living skin. In addition, 50-MHz ultrasound images and histological pictures are presented for comparison with OCT.

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Optical coherence - Gated imaging of biological tissues

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