TY - GEN
T1 - Optical tomographic imaging of small tissue volumes
T2 - 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, ISBI 2004
AU - Hielscher, A. H.
AU - Klose, A. D.
AU - Scheel, A.
AU - Bluestone, A.
AU - Lasker, J. M.
AU - Moa-Anderson, B.
AU - Masciotti, J. M.
AU - Netz, U.
AU - Beuthan, J.
AU - Stewart, M.
AU - Abdoulaev, G.
PY - 2004
Y1 - 2004
N2 - Over the last decade the field of diffuse optical tomography (DOT) has seen considerable advances and is now close to becoming a clinically viable medical imaging modality. Imaging of dynamic changes in blood parameters, functional brain imaging, and breast imaging are the most advanced application areas of this novel technique. In this study we focus on difficulties that are encountered when DOT is employed for imaging small tissue volumes. These problems arise, for example, in studies involving small animals, such as rats or mice, or human finger joints. In these cases widely accepted image reconstruction schemes that rely on the diffusion approximation have limited applicability, and more advanced model-based iterative image reconstructions methods that make use of the equation of radiative transfer promise more accurate results.
AB - Over the last decade the field of diffuse optical tomography (DOT) has seen considerable advances and is now close to becoming a clinically viable medical imaging modality. Imaging of dynamic changes in blood parameters, functional brain imaging, and breast imaging are the most advanced application areas of this novel technique. In this study we focus on difficulties that are encountered when DOT is employed for imaging small tissue volumes. These problems arise, for example, in studies involving small animals, such as rats or mice, or human finger joints. In these cases widely accepted image reconstruction schemes that rely on the diffusion approximation have limited applicability, and more advanced model-based iterative image reconstructions methods that make use of the equation of radiative transfer promise more accurate results.
UR - https://www.scopus.com/pages/publications/20244375710
U2 - 10.1109/ISBI.2004.1398826
DO - 10.1109/ISBI.2004.1398826
M3 - Conference contribution
AN - SCOPUS:20244375710
SN - 0780383885
SN - 9780780383883
T3 - 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
SP - 1467
EP - 1470
BT - 2004 2nd IEEE International Symposium on Biomedical Imaging
PB - Institute of Electrical and Electronics Engineers Inc.
Y2 - 18 April 2004 through 18 April 2004
ER -