Abstract
In clinical trials involving several treatment protocols, there are usually several objectives of different importance. A general method for finding an optimal design which reflects this practical need is discussed. In particular, we show that the graphical method of Cook and Wong can be applied when there are two objectives. Several illustrative examples are discussed, including multiple-objective designs for comparing several treatment groups with a placebo group. Copyright (C) 2000 John Wiley and Sons, Ltd.
| Original language | English |
|---|---|
| Pages (from-to) | 639-648 |
| Number of pages | 10 |
| Journal | Statistics in Medicine |
| Volume | 19 |
| Issue number | 5 |
| DOIs | |
| State | Published - Mar 15 2000 |
Fingerprint
Dive into the research topics of 'Optimal treatment allocation in comparative biomedical studies'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver