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Ozone therapy for diabetic foot

  • Robert Kushmakov
  • , Jason Gandhi
  • , Omar Seyam
  • , Wendy Jiang
  • , Gunjan Joshi
  • , Noel L. Smith
  • , Sardar Ali Khan
  • Stony Brook University
  • St. George's University Grenada
  • Foley Plaza Medical

Research output: Contribution to journalReview articlepeer-review

36 Scopus citations

Abstract

Diabetic foot ulcers (DFU) are a burden to the diabetic community. With increasing medical bills, to unsuccessful treatment, those suffering from DFUs can use alternative therapeutics. First seen in the mid-1800s, ozone (O3) is thought to be unstable, due to inherent molecular nature. With the help of pharmaceutical science, various O3 treatments have flourished in the medical community to help those suffering from DFUs. Promising results are seen through numerous studies. Usually, a mixture of both O2 and O3 is seen in pressurized machines as administered to the foot ulcer. Foot ulcers, specifically DFUs, need to be assessed, cleaned, and treated as fast as possible for the fastest results. Results such as amputation can be seen if the foot is not attended to as soon as possible. With fast growing clinical trials in O3 therapy and quick administration of the O3, O3 therapy may be on the rise to be at the forefront of treating DFUs. Compelling evidence is seen in clinical trials, but more must be done to fully understand the role of O3 in DFUs.

Original languageEnglish
Pages (from-to)111-115
Number of pages5
JournalMedical Gas Research
Volume8
Issue number3
DOIs
StatePublished - Jul 1 2018

Keywords

  • Charcot foot
  • diabetes mellitus
  • diabetic foot ulcer
  • oxygen-ozone
  • ozone therapy
  • peripheral arterial disease
  • wound closure
  • wound healing

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