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PDT induced changes assessed by time-gated fluorescence tomography in a head and neck tumor model

  • Roswell Park Cancer Institute

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

We report the simultaneous 3D reconstruction of fluorescence yield and lifetime of a photosensitizer (HPPH) before and after PDT. HPPH-mediated PDT induced significant changes in fluorescence yield and lifetime. This pilot study demonstrates that time-domain fluorescence tomography may be useful for assessing photosensitizer distributions in deep tissue during PDT monitoring.

Original languageEnglish
Title of host publicationBiomedical Optics, BIOMED 2012
PublisherOptical Society of America (OSA)
PagesBSu5A.9
ISBN (Print)9781557529428
DOIs
StatePublished - 2012
EventBiomedical Optics, BIOMED 2012 - Miami, FL, United States
Duration: Apr 28 2012May 2 2012

Publication series

NameBiomedical Optics, BIOMED 2012

Conference

ConferenceBiomedical Optics, BIOMED 2012
Country/TerritoryUnited States
CityMiami, FL
Period04/28/1205/2/12

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