Persistent Legionnaire's disease in an adult with hairy cell leukemia successfully treated with prolonged levofloxacin therapy

Burke A. Cunha; Sigridh Munoz-Gomez; Arthur Gran; Muhammad Raza; Nadia Irshad

doi:10.1016/j.hrtlng.2015.04.009

Persistent Legionnaire's disease in an adult with hairy cell leukemia successfully treated with prolonged levofloxacin therapy

Burke A. Cunha
, Sigridh Munoz-Gomez
, Arthur Gran
, Muhammad Raza
, Nadia Irshad

Geriatric and General Medicine

Winthrop-University Hospital
Stony Brook University

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Legionnaire's disease (LD) manifests most commonly as an atypical community acquired pneumonia (CAP) with systemic extrapulmonary manifestations. Disorders associated with impaired cell mediated immunity (CMI) are particularly predisposed to LD. Hairy cell leukemia (HCL) is a rare B-cell lymphoproliferative leukemia associated with decreased CMI. LD has only rarely been reported in HCL. We present a most interesting case of persistent LD in a elderly male with HCL who required prolonged antibiotic therapy.

Original language	English
Pages (from-to)	360-362
Number of pages	3
Journal	Heart and Lung: Journal of Acute and Critical Care
Volume	44
Issue number	4
DOIs	https://doi.org/10.1016/j.hrtlng.2015.04.009
State	Published - Jul 1 2015

Keywords

Clinical diagnosis of Legionnaire's disease
Legionnaire's disease atypical pneumonia
Legionnaire's disease in compromised hosts
Legionnaire's disease therapy
Oral antibiotic therapy

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10.1016/j.hrtlng.2015.04.009

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title = "Persistent Legionnaire's disease in an adult with hairy cell leukemia successfully treated with prolonged levofloxacin therapy",

abstract = "Legionnaire's disease (LD) manifests most commonly as an atypical community acquired pneumonia (CAP) with systemic extrapulmonary manifestations. Disorders associated with impaired cell mediated immunity (CMI) are particularly predisposed to LD. Hairy cell leukemia (HCL) is a rare B-cell lymphoproliferative leukemia associated with decreased CMI. LD has only rarely been reported in HCL. We present a most interesting case of persistent LD in a elderly male with HCL who required prolonged antibiotic therapy.",

keywords = "Clinical diagnosis of Legionnaire's disease, Legionnaire's disease atypical pneumonia, Legionnaire's disease in compromised hosts, Legionnaire's disease therapy, Oral antibiotic therapy",

author = "Cunha, \{Burke A.\} and Sigridh Munoz-Gomez and Arthur Gran and Muhammad Raza and Nadia Irshad",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2015",

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doi = "10.1016/j.hrtlng.2015.04.009",

language = "English",

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T1 - Persistent Legionnaire's disease in an adult with hairy cell leukemia successfully treated with prolonged levofloxacin therapy

AU - Cunha, Burke A.

AU - Munoz-Gomez, Sigridh

AU - Gran, Arthur

AU - Raza, Muhammad

AU - Irshad, Nadia

PY - 2015/7/1

Y1 - 2015/7/1

N2 - Legionnaire's disease (LD) manifests most commonly as an atypical community acquired pneumonia (CAP) with systemic extrapulmonary manifestations. Disorders associated with impaired cell mediated immunity (CMI) are particularly predisposed to LD. Hairy cell leukemia (HCL) is a rare B-cell lymphoproliferative leukemia associated with decreased CMI. LD has only rarely been reported in HCL. We present a most interesting case of persistent LD in a elderly male with HCL who required prolonged antibiotic therapy.

AB - Legionnaire's disease (LD) manifests most commonly as an atypical community acquired pneumonia (CAP) with systemic extrapulmonary manifestations. Disorders associated with impaired cell mediated immunity (CMI) are particularly predisposed to LD. Hairy cell leukemia (HCL) is a rare B-cell lymphoproliferative leukemia associated with decreased CMI. LD has only rarely been reported in HCL. We present a most interesting case of persistent LD in a elderly male with HCL who required prolonged antibiotic therapy.

KW - Clinical diagnosis of Legionnaire's disease

KW - Legionnaire's disease atypical pneumonia

KW - Legionnaire's disease in compromised hosts

KW - Legionnaire's disease therapy

KW - Oral antibiotic therapy

UR - https://www.scopus.com/pages/publications/84930822834

U2 - 10.1016/j.hrtlng.2015.04.009

DO - 10.1016/j.hrtlng.2015.04.009

M3 - Article

C2 - 26021547

AN - SCOPUS:84930822834

SN - 0147-9563

VL - 44

SP - 360

EP - 362

JO - Heart and Lung: Journal of Acute and Critical Care

JF - Heart and Lung: Journal of Acute and Critical Care

IS - 4

ER -

Persistent Legionnaire's disease in an adult with hairy cell leukemia successfully treated with prolonged levofloxacin therapy

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