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Polyelectrolytes for cell encapsulation

  • University of Massachusetts

Research output: Contribution to journalReview articlepeer-review

130 Scopus citations

Abstract

Recent advances in the use of polyelectrolyte materials for cell encapsulation are reviewed, with a focus on three current challenges: tunable mechanical properties, controlled cell adhesion, and enhanced oxygen supply. New notable results include methods for creating stable alginate-silica complexes, techniques for incorporating RGD-containing peptides into alginate gels, and an improved understanding of the effect of charge density on cell-material interactions.

Original languageEnglish
Pages (from-to)45-51
Number of pages7
JournalCurrent Opinion in Colloid and Interface Science
Volume10
Issue number1-2
DOIs
StatePublished - Aug 2005

Keywords

  • Alginate
  • Immunoprotective membranes
  • Polyelectrolyte complexes
  • Polyelectrolyte gels
  • Tissue engineering

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