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Position Paper: Artificial Intelligence in Medical Image Analysis: Advances, Clinical Translation, and Emerging Frontiers

  • A. S. Panayides
  • , H. Chen
  • , N. D. Filipovic
  • , T. Geroski
  • , J. Hou
  • , K. Lekadir
  • , K. Marias
  • , G. K. Matsopoulos
  • , G. Papanastasiou
  • , P. Sarder
  • , G. Tourassi
  • , S. A. Tsaftaris
  • , H. Fu
  • , E. Kyriacou
  • , C. P. Loizou
  • , M. Zervakis
  • , J. H. Saltz
  • , F. E. Shamout
  • , K. C.L. Wong
  • , J. Yao
  • A. Amini, D. I. Fotiadis, C. S. Pattichis, M. S. Pattichis
  • CYENS Centre of Excellence
  • Hong Kong University of Science and Technology
  • University of Kragujevac
  • University of Barcelona
  • Hellenic Mediterranean University
  • National Technical University of Athens
  • Academy of Athens
  • University of Florida
  • Oak Ridge National Laboratory
  • University of Edinburgh
  • Athena Research Centre
  • Agency for Science, Technology and Research, Singapore
  • Cyprus University of Technology
  • Technical University of Crete
  • New York University Abu Dhabi
  • IBM
  • Tencent
  • University of Louisville
  • University of Ioannina
  • University of Cyprus
  • University of New Mexico

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Over the past five years, artificial intelligence (AI) has introduced new models and methods for addressing the challenges associated with the broader adoption of AI models and systems in medicine. This paper reviews recent advances in AI for medical image and video analysis, outlines emerging paradigms, highlights pathways for successful clinical translation, and provides recommendations for future work. Hybrid Convolutional Neural Network (CNN) Transformer architectures now deliver state-of-the-art results in segmentation, classification, reconstruction, synthesis, and registration. Foundation and generative AI models enable the use of transfer learning to smaller datasets with limited ground truth. Federated learning supports privacy-preserving collaboration across institutions. Explainable and trustworthy AI approaches have become essential to foster clinician trust, ensure regulatory compliance, and facilitate ethical deployment. Together, these developments pave the way for integrating AI into radiology, pathology, and wider healthcare workflows.

Original languageEnglish
Pages (from-to)1187-1202
Number of pages16
JournalIEEE Journal of Biomedical and Health Informatics
Volume30
Issue number2
DOIs
StatePublished - Feb 2026

Keywords

  • Artificial intelligence (AI)
  • clinical workflow integration
  • computational pathology
  • convolutional neural networks (CNNs)
  • ethics
  • explainable AI
  • federated learning
  • foundation models
  • generative AI
  • medical imaging
  • medical video analysis
  • medical video analysis
  • multimodal fusion
  • regulatory compliance
  • transformers
  • trustworthy AI

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