Presence of catecholaminergic axon-terminals containing β-adrenergic receptor in the periventricular zone of the rat hypothalamus

Akio Wanaka; Craig C. Malbon; Masayasu Matsumoto; Takenobu Kamada; Masaya Tohyama

doi:10.1016/0006-8993(89)91352-8

Presence of catecholaminergic axon-terminals containing β-adrenergic receptor in the periventricular zone of the rat hypothalamus

Akio Wanaka
, Craig C. Malbon
, Masayasu Matsumoto
, Takenobu Kamada
, Masaya Tohyama

Pharmacological Sciences

The University of Osaka

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The present study, using a light microscopic double-immunofluorescence method, has revealed the presence of fibers containing both tyrosine hydroxylase- and β-adrenergic receptor-like immunoreactivities in the rat hypothalamic periventricular zone. Subsequent immunoelectron microscopic analysis demonstrated that these belong to axon terminals. These findings suggest that presynaptic β-adrenergic receptor is present in catecholaminergic terminals.

Original language	English
Pages (from-to)	190-193
Number of pages	4
Journal	Brain Research
Volume	479
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(89)91352-8
State	Published - Feb 6 1989

Keywords

Hypothalamus
Immunoelectron microscopy
Presynaptic autoreceptor
β-Adrenergic receptor

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10.1016/0006-8993(89)91352-8

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title = "Presence of catecholaminergic axon-terminals containing β-adrenergic receptor in the periventricular zone of the rat hypothalamus",

abstract = "The present study, using a light microscopic double-immunofluorescence method, has revealed the presence of fibers containing both tyrosine hydroxylase- and β-adrenergic receptor-like immunoreactivities in the rat hypothalamic periventricular zone. Subsequent immunoelectron microscopic analysis demonstrated that these belong to axon terminals. These findings suggest that presynaptic β-adrenergic receptor is present in catecholaminergic terminals.",

keywords = "Hypothalamus, Immunoelectron microscopy, Presynaptic autoreceptor, β-Adrenergic receptor",

author = "Akio Wanaka and Malbon, \{Craig C.\} and Masayasu Matsumoto and Takenobu Kamada and Masaya Tohyama",

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T1 - Presence of catecholaminergic axon-terminals containing β-adrenergic receptor in the periventricular zone of the rat hypothalamus

AU - Wanaka, Akio

AU - Malbon, Craig C.

AU - Matsumoto, Masayasu

AU - Kamada, Takenobu

AU - Tohyama, Masaya

PY - 1989/2/6

Y1 - 1989/2/6

N2 - The present study, using a light microscopic double-immunofluorescence method, has revealed the presence of fibers containing both tyrosine hydroxylase- and β-adrenergic receptor-like immunoreactivities in the rat hypothalamic periventricular zone. Subsequent immunoelectron microscopic analysis demonstrated that these belong to axon terminals. These findings suggest that presynaptic β-adrenergic receptor is present in catecholaminergic terminals.

AB - The present study, using a light microscopic double-immunofluorescence method, has revealed the presence of fibers containing both tyrosine hydroxylase- and β-adrenergic receptor-like immunoreactivities in the rat hypothalamic periventricular zone. Subsequent immunoelectron microscopic analysis demonstrated that these belong to axon terminals. These findings suggest that presynaptic β-adrenergic receptor is present in catecholaminergic terminals.

KW - Hypothalamus

KW - Immunoelectron microscopy

KW - Presynaptic autoreceptor

KW - β-Adrenergic receptor

UR - https://www.scopus.com/pages/publications/0024537943

U2 - 10.1016/0006-8993(89)91352-8

DO - 10.1016/0006-8993(89)91352-8

M3 - Article

C2 - 2564305

AN - SCOPUS:0024537943

SN - 0006-8993

VL - 479

SP - 190

EP - 193

JO - Brain Research

JF - Brain Research

IS - 1

ER -

Presence of catecholaminergic axon-terminals containing β-adrenergic receptor in the periventricular zone of the rat hypothalamus

Abstract

Keywords

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