Prospective Epidemiological Research Studies in Iran (the PERSIAN Cohort Study): Rationale, Objectives, and Design

Hossein Poustchi; Sareh Eghtesad; Farin Kamangar; Arash Etemadi; Abbas Ali Keshtkar; Azita Hekmatdoost; Zahra Mohammadi; Zahra Mahmoudi; Amaneh Shayanrad; Farzin Roozafzai; Mahdi Sheikh; Alireza Jalaeikhoo; Mohammad Hossein Somi; Fariborz Mansour-Ghanaei; Farid Najafi; Ehsan Bahramali; Amirhoushang Mehrparvar; Alireza Ansari-Moghaddam; Ahmad Ali Enayati; Ali Esmaeili Nadimi; Abbas Rezaianzadeh; Nader Saki; Fatemeh Alipour; Roya Kelishadi; Afarin Rahimi-Movaghar; Nayyereh Aminisani; Paolo Boffetta; Reza Malekzadeh

doi:10.1093/aje/kwx314

Prospective Epidemiological Research Studies in Iran (the PERSIAN Cohort Study): Rationale, Objectives, and Design

Hossein Poustchi
, Sareh Eghtesad
, Farin Kamangar
, Arash Etemadi
, Abbas Ali Keshtkar
, Azita Hekmatdoost
, Zahra Mohammadi
, Zahra Mahmoudi
, Amaneh Shayanrad
, Farzin Roozafzai
, Mahdi Sheikh
, Alireza Jalaeikhoo
, Mohammad Hossein Somi
, Fariborz Mansour-Ghanaei
, Farid Najafi
, Ehsan Bahramali
, Amirhoushang Mehrparvar
, Alireza Ansari-Moghaddam
, Ahmad Ali Enayati
, Ali Esmaeili Nadimi

Abbas Rezaianzadeh, Nader Saki, Fatemeh Alipour, Roya Kelishadi, Afarin Rahimi-Movaghar, Nayyereh Aminisani, Paolo Boffetta, Reza Malekzadeh

Family , Population and Preventative Medicine

Tehran University of Medical Sciences
Morgan State University
National Institutes of Health
Tabriz University of Medical Sciences
Guilan University of Medical Sciences
Kermanshah University of Medical Sciences
Fasa UMS
Shahid Sadoughi UMS
Zahedan University of Medical Sciences
Mazandaran University of Medical Sciences
School of Medicine
Shiraz University of Medical Sciences
Hearing and Speech Research Center
Isfahan University of Medical Sciences

Research output: Contribution to journal › Article › peer-review

607 Scopus citations

Abstract

Noncommunicable diseases (NCDs) account for 76% of deaths in Iran, and this number is on the rise, in parallel with global rates. Many risk factors associated with NCDs are preventable; however, it is first necessary to conduct observational studies to identify relevant risk factors and the most appropriate approach to controlling them. Iran is a multiethnic country; therefore, in 2014 the Ministry of Health and Medical Education launched a nationwide cohort study - Prospective Epidemiological Research Studies in Iran (PERSIAN) - in order to identify the most prevalent NCDs among Iran's ethnic groups and to investigate effective methods of prevention. The PERSIAN study consists of 4 population-based cohorts; the adult component (the PERSIAN Cohort Study), described in this article, is a prospective cohort study including 180,000 persons aged 35-70 years from 18 distinct areas of Iran. Upon joining the cohort, participants respond to interviewer-administered questionnaires. Blood, urine, hair, and nail samples are collected and stored. To ensure consistency, centrally purchased equipment is sent to all sites, and the same team trains all personnel. Routine visits and quality assurance/control measures are taken to ensure protocol adherence. Participants are followed for 15 years postenrollment. The PERSIAN study is currently in the enrollment phase; cohort profiles will soon emerge.

Original language	English
Pages (from-to)	647-655
Number of pages	9
Journal	American Journal of Epidemiology
Volume	187
Issue number	4
DOIs	https://doi.org/10.1093/aje/kwx314
State	Published - Apr 1 2018

Keywords

cohort studies
Iran
noncommunicable diseases
Prospective Epidemiological Research Studies in Iran (PERSIAN)

Access to Document

10.1093/aje/kwx314

Cite this

Poustchi, H., Eghtesad, S., Kamangar, F., Etemadi, A., Keshtkar, A. A., Hekmatdoost, A., Mohammadi, Z., Mahmoudi, Z., Shayanrad, A., Roozafzai, F., Sheikh, M., Jalaeikhoo, A., Somi, M. H., Mansour-Ghanaei, F., Najafi, F., Bahramali, E., Mehrparvar, A., Ansari-Moghaddam, A., Enayati, A. A., ... Malekzadeh, R. (2018). Prospective Epidemiological Research Studies in Iran (the PERSIAN Cohort Study): Rationale, Objectives, and Design. American Journal of Epidemiology, 187(4), 647-655. https://doi.org/10.1093/aje/kwx314

@article{87c1bf1bd52d49d4bfe40d847c8c74e0,

title = "Prospective Epidemiological Research Studies in Iran (the PERSIAN Cohort Study): Rationale, Objectives, and Design",

abstract = "Noncommunicable diseases (NCDs) account for 76\% of deaths in Iran, and this number is on the rise, in parallel with global rates. Many risk factors associated with NCDs are preventable; however, it is first necessary to conduct observational studies to identify relevant risk factors and the most appropriate approach to controlling them. Iran is a multiethnic country; therefore, in 2014 the Ministry of Health and Medical Education launched a nationwide cohort study - Prospective Epidemiological Research Studies in Iran (PERSIAN) - in order to identify the most prevalent NCDs among Iran's ethnic groups and to investigate effective methods of prevention. The PERSIAN study consists of 4 population-based cohorts; the adult component (the PERSIAN Cohort Study), described in this article, is a prospective cohort study including 180,000 persons aged 35-70 years from 18 distinct areas of Iran. Upon joining the cohort, participants respond to interviewer-administered questionnaires. Blood, urine, hair, and nail samples are collected and stored. To ensure consistency, centrally purchased equipment is sent to all sites, and the same team trains all personnel. Routine visits and quality assurance/control measures are taken to ensure protocol adherence. Participants are followed for 15 years postenrollment. The PERSIAN study is currently in the enrollment phase; cohort profiles will soon emerge.",

keywords = "cohort studies, Iran, noncommunicable diseases, Prospective Epidemiological Research Studies in Iran (PERSIAN)",

author = "Hossein Poustchi and Sareh Eghtesad and Farin Kamangar and Arash Etemadi and Keshtkar, \{Abbas Ali\} and Azita Hekmatdoost and Zahra Mohammadi and Zahra Mahmoudi and Amaneh Shayanrad and Farzin Roozafzai and Mahdi Sheikh and Alireza Jalaeikhoo and Somi, \{Mohammad Hossein\} and Fariborz Mansour-Ghanaei and Farid Najafi and Ehsan Bahramali and Amirhoushang Mehrparvar and Alireza Ansari-Moghaddam and Enayati, \{Ahmad Ali\} and \{Esmaeili Nadimi\}, Ali and Abbas Rezaianzadeh and Nader Saki and Fatemeh Alipour and Roya Kelishadi and Afarin Rahimi-Movaghar and Nayyereh Aminisani and Paolo Boffetta and Reza Malekzadeh",

year = "2018",

month = apr,

day = "1",

doi = "10.1093/aje/kwx314",

language = "English",

volume = "187",

pages = "647--655",

journal = "American Journal of Epidemiology",

issn = "0002-9262",

number = "4",

}

Poustchi, H, Eghtesad, S, Kamangar, F, Etemadi, A, Keshtkar, AA, Hekmatdoost, A, Mohammadi, Z, Mahmoudi, Z, Shayanrad, A, Roozafzai, F, Sheikh, M, Jalaeikhoo, A, Somi, MH, Mansour-Ghanaei, F, Najafi, F, Bahramali, E, Mehrparvar, A, Ansari-Moghaddam, A, Enayati, AA, Esmaeili Nadimi, A, Rezaianzadeh, A, Saki, N, Alipour, F, Kelishadi, R, Rahimi-Movaghar, A, Aminisani, N, Boffetta, P & Malekzadeh, R 2018, 'Prospective Epidemiological Research Studies in Iran (the PERSIAN Cohort Study): Rationale, Objectives, and Design', American Journal of Epidemiology, vol. 187, no. 4, pp. 647-655. https://doi.org/10.1093/aje/kwx314

TY - JOUR

T1 - Prospective Epidemiological Research Studies in Iran (the PERSIAN Cohort Study)

T2 - Rationale, Objectives, and Design

AU - Poustchi, Hossein

AU - Eghtesad, Sareh

AU - Kamangar, Farin

AU - Etemadi, Arash

AU - Keshtkar, Abbas Ali

AU - Hekmatdoost, Azita

AU - Mohammadi, Zahra

AU - Mahmoudi, Zahra

AU - Shayanrad, Amaneh

AU - Roozafzai, Farzin

AU - Sheikh, Mahdi

AU - Jalaeikhoo, Alireza

AU - Somi, Mohammad Hossein

AU - Mansour-Ghanaei, Fariborz

AU - Najafi, Farid

AU - Bahramali, Ehsan

AU - Mehrparvar, Amirhoushang

AU - Ansari-Moghaddam, Alireza

AU - Enayati, Ahmad Ali

AU - Esmaeili Nadimi, Ali

AU - Rezaianzadeh, Abbas

AU - Saki, Nader

AU - Alipour, Fatemeh

AU - Kelishadi, Roya

AU - Rahimi-Movaghar, Afarin

AU - Aminisani, Nayyereh

AU - Boffetta, Paolo

AU - Malekzadeh, Reza

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Noncommunicable diseases (NCDs) account for 76% of deaths in Iran, and this number is on the rise, in parallel with global rates. Many risk factors associated with NCDs are preventable; however, it is first necessary to conduct observational studies to identify relevant risk factors and the most appropriate approach to controlling them. Iran is a multiethnic country; therefore, in 2014 the Ministry of Health and Medical Education launched a nationwide cohort study - Prospective Epidemiological Research Studies in Iran (PERSIAN) - in order to identify the most prevalent NCDs among Iran's ethnic groups and to investigate effective methods of prevention. The PERSIAN study consists of 4 population-based cohorts; the adult component (the PERSIAN Cohort Study), described in this article, is a prospective cohort study including 180,000 persons aged 35-70 years from 18 distinct areas of Iran. Upon joining the cohort, participants respond to interviewer-administered questionnaires. Blood, urine, hair, and nail samples are collected and stored. To ensure consistency, centrally purchased equipment is sent to all sites, and the same team trains all personnel. Routine visits and quality assurance/control measures are taken to ensure protocol adherence. Participants are followed for 15 years postenrollment. The PERSIAN study is currently in the enrollment phase; cohort profiles will soon emerge.

AB - Noncommunicable diseases (NCDs) account for 76% of deaths in Iran, and this number is on the rise, in parallel with global rates. Many risk factors associated with NCDs are preventable; however, it is first necessary to conduct observational studies to identify relevant risk factors and the most appropriate approach to controlling them. Iran is a multiethnic country; therefore, in 2014 the Ministry of Health and Medical Education launched a nationwide cohort study - Prospective Epidemiological Research Studies in Iran (PERSIAN) - in order to identify the most prevalent NCDs among Iran's ethnic groups and to investigate effective methods of prevention. The PERSIAN study consists of 4 population-based cohorts; the adult component (the PERSIAN Cohort Study), described in this article, is a prospective cohort study including 180,000 persons aged 35-70 years from 18 distinct areas of Iran. Upon joining the cohort, participants respond to interviewer-administered questionnaires. Blood, urine, hair, and nail samples are collected and stored. To ensure consistency, centrally purchased equipment is sent to all sites, and the same team trains all personnel. Routine visits and quality assurance/control measures are taken to ensure protocol adherence. Participants are followed for 15 years postenrollment. The PERSIAN study is currently in the enrollment phase; cohort profiles will soon emerge.

KW - cohort studies

KW - Iran

KW - noncommunicable diseases

KW - Prospective Epidemiological Research Studies in Iran (PERSIAN)

UR - https://www.scopus.com/pages/publications/85042090127

U2 - 10.1093/aje/kwx314

DO - 10.1093/aje/kwx314

M3 - Article

C2 - 29145581

AN - SCOPUS:85042090127

SN - 0002-9262

VL - 187

SP - 647

EP - 655

JO - American Journal of Epidemiology

JF - American Journal of Epidemiology

IS - 4

ER -

Prospective Epidemiological Research Studies in Iran (the PERSIAN Cohort Study): Rationale, Objectives, and Design

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this