Reduction of carbonyl compounds via hydrosilylation. II. Asymmetric reduction of ketones via hydrosilylation catalyzed by a rhodium(I) complex with chiral phosphine ligands

Iwao Ojima; Tetsuo Kogure; Miyoko Kumagai; Shuji Horiuchi; Toshikazu Sato

doi:10.1016/S0022-328X(00)92750-5

Reduction of carbonyl compounds via hydrosilylation. II. Asymmetric reduction of ketones via hydrosilylation catalyzed by a rhodium(I) complex with chiral phosphine ligands

Iwao Ojima
, Tetsuo Kogure
, Miyoko Kumagai
, Shuji Horiuchi
, Toshikazu Sato

Chemistry

Sagami Chemical Research Institute

Research output: Contribution to journal › Article › peer-review

131 Scopus citations

Abstract

Effective asymmetric reduction of alkyl phenyl, dialkyl and alkyl cyclohexyl ketones has been achieved via hydrosilylation, catalyzed by a rhodium(I) complex with optically active phosphine ligands using various hydrosilanes. A mechanism of the induction of asymmetry is proposed in view of the stereochemical course of the reaction.

Original language	English
Pages (from-to)	83-97
Number of pages	15
Journal	Journal of Organometallic Chemistry
Volume	122
Issue number	1
DOIs	https://doi.org/10.1016/S0022-328X(00)92750-5
State	Published - Dec 7 1976

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10.1016/S0022-328X(00)92750-5

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title = "Reduction of carbonyl compounds via hydrosilylation. II. Asymmetric reduction of ketones via hydrosilylation catalyzed by a rhodium(I) complex with chiral phosphine ligands",

abstract = "Effective asymmetric reduction of alkyl phenyl, dialkyl and alkyl cyclohexyl ketones has been achieved via hydrosilylation, catalyzed by a rhodium(I) complex with optically active phosphine ligands using various hydrosilanes. A mechanism of the induction of asymmetry is proposed in view of the stereochemical course of the reaction.",

author = "Iwao Ojima and Tetsuo Kogure and Miyoko Kumagai and Shuji Horiuchi and Toshikazu Sato",

year = "1976",

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language = "English",

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pages = "83--97",

journal = "Journal of Organometallic Chemistry",

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Reduction of carbonyl compounds via hydrosilylation. II. Asymmetric reduction of ketones via hydrosilylation catalyzed by a rhodium(I) complex with chiral phosphine ligands. / Ojima, Iwao; Kogure, Tetsuo; Kumagai, Miyoko et al.
In: Journal of Organometallic Chemistry, Vol. 122, No. 1, 07.12.1976, p. 83-97.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Reduction of carbonyl compounds via hydrosilylation. II. Asymmetric reduction of ketones via hydrosilylation catalyzed by a rhodium(I) complex with chiral phosphine ligands

AU - Ojima, Iwao

AU - Kogure, Tetsuo

AU - Kumagai, Miyoko

AU - Horiuchi, Shuji

AU - Sato, Toshikazu

PY - 1976/12/7

Y1 - 1976/12/7

N2 - Effective asymmetric reduction of alkyl phenyl, dialkyl and alkyl cyclohexyl ketones has been achieved via hydrosilylation, catalyzed by a rhodium(I) complex with optically active phosphine ligands using various hydrosilanes. A mechanism of the induction of asymmetry is proposed in view of the stereochemical course of the reaction.

AB - Effective asymmetric reduction of alkyl phenyl, dialkyl and alkyl cyclohexyl ketones has been achieved via hydrosilylation, catalyzed by a rhodium(I) complex with optically active phosphine ligands using various hydrosilanes. A mechanism of the induction of asymmetry is proposed in view of the stereochemical course of the reaction.

UR - https://www.scopus.com/pages/publications/0001925753

U2 - 10.1016/S0022-328X(00)92750-5

DO - 10.1016/S0022-328X(00)92750-5

M3 - Article

AN - SCOPUS:0001925753

SN - 0022-328X

VL - 122

SP - 83

EP - 97

JO - Journal of Organometallic Chemistry

JF - Journal of Organometallic Chemistry

IS - 1

ER -

Reduction of carbonyl compounds via hydrosilylation. II. Asymmetric reduction of ketones via hydrosilylation catalyzed by a rhodium(I) complex with chiral phosphine ligands

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