TY - GEN
T1 - Restoring the invisible details in differential interference contrast microscopy images
AU - Jiang, Wenchao
AU - Yin, Zhaozheng
N1 - Publisher Copyright:
© Springer International Publishing Switzerland 2015.
PY - 2015
Y1 - 2015
N2 - Automated image restoration in microscopy, especially in Differential Interference Contrast (DIC) imaging modality, has attracted increasing attention since it greatly facilitates living cell analysis. Previous work is able to restore the nuclei of living cells, but it is very challenging to reconstruct the unnoticeable cytoplasm details in DIC images. In this paper, we propose to extract the tiny movement information of living cells in DIC images and reveal the hidden details in DIC images by magnifying the cell’s motion as well as attenuating the intensity variation from the background. From our restored images, we can clearly observe the previously-invisible details in DIC images. Experiments on two DIC image datasets demonstrate that the motion-based restoration method can reveal the hidden details of living cells, providing promising results on facilitating cell shape and behavior analysis.
AB - Automated image restoration in microscopy, especially in Differential Interference Contrast (DIC) imaging modality, has attracted increasing attention since it greatly facilitates living cell analysis. Previous work is able to restore the nuclei of living cells, but it is very challenging to reconstruct the unnoticeable cytoplasm details in DIC images. In this paper, we propose to extract the tiny movement information of living cells in DIC images and reveal the hidden details in DIC images by magnifying the cell’s motion as well as attenuating the intensity variation from the background. From our restored images, we can clearly observe the previously-invisible details in DIC images. Experiments on two DIC image datasets demonstrate that the motion-based restoration method can reveal the hidden details of living cells, providing promising results on facilitating cell shape and behavior analysis.
UR - https://www.scopus.com/pages/publications/84951823732
U2 - 10.1007/978-3-319-24574-4_41
DO - 10.1007/978-3-319-24574-4_41
M3 - Conference contribution
AN - SCOPUS:84951823732
SN - 9783319245737
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 340
EP - 348
BT - Medical Image Computing and Computer-Assisted Intervention – MICCAI 2015 - 18th International Conference, Proceedings
A2 - Frangi, Alejandro F.
A2 - Navab, Nassir
A2 - Hornegger, Joachim
A2 - Wells, William M.
PB - Springer Verlag
T2 - 18th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2015
Y2 - 5 October 2015 through 9 October 2015
ER -