Role for the oxyS gene in regulation of intracellular hydrogen peroxide in Escherichia coli

Beatriz González-Flecha; Bruce Demple

doi:10.1128/jb.181.12.3833-3836.1999

Role for the oxyS gene in regulation of intracellular hydrogen peroxide in Escherichia coli

Beatriz González-Flecha
, Bruce Demple

Pharmacological Sciences

Harvard University
Physiology Program

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

Intracellular hydrogen peroxide is regulated in Escherichia coli by OxyR in response to the metabolic production of H₂O₂. Here, we show that the untranslated oxyS RNA controlled by OxyR has a role in this regulation. The oxyS transcript appears to affect the metabolic output of H₂O₂ rather than the removal of H₂O₂ by catalases-hydroperoxidases.

Original language	English
Pages (from-to)	3833-3836
Number of pages	4
Journal	Journal of Bacteriology
Volume	181
Issue number	12
DOIs	https://doi.org/10.1128/jb.181.12.3833-3836.1999
State	Published - Jun 1999

Access to Document

10.1128/jb.181.12.3833-3836.1999

Cite this

@article{4de615ba834241f7b169b1b61f13bc35,

title = "Role for the oxyS gene in regulation of intracellular hydrogen peroxide in Escherichia coli",

abstract = "Intracellular hydrogen peroxide is regulated in Escherichia coli by OxyR in response to the metabolic production of H2O2. Here, we show that the untranslated oxyS RNA controlled by OxyR has a role in this regulation. The oxyS transcript appears to affect the metabolic output of H2O2 rather than the removal of H2O2 by catalases-hydroperoxidases.",

author = "Beatriz Gonz{\'a}lez-Flecha and Bruce Demple",

year = "1999",

month = jun,

doi = "10.1128/jb.181.12.3833-3836.1999",

language = "English",

volume = "181",

pages = "3833--3836",

journal = "Journal of Bacteriology",

issn = "0021-9193",

number = "12",

}

TY - JOUR

T1 - Role for the oxyS gene in regulation of intracellular hydrogen peroxide in Escherichia coli

AU - González-Flecha, Beatriz

AU - Demple, Bruce

PY - 1999/6

Y1 - 1999/6

N2 - Intracellular hydrogen peroxide is regulated in Escherichia coli by OxyR in response to the metabolic production of H2O2. Here, we show that the untranslated oxyS RNA controlled by OxyR has a role in this regulation. The oxyS transcript appears to affect the metabolic output of H2O2 rather than the removal of H2O2 by catalases-hydroperoxidases.

AB - Intracellular hydrogen peroxide is regulated in Escherichia coli by OxyR in response to the metabolic production of H2O2. Here, we show that the untranslated oxyS RNA controlled by OxyR has a role in this regulation. The oxyS transcript appears to affect the metabolic output of H2O2 rather than the removal of H2O2 by catalases-hydroperoxidases.

UR - https://www.scopus.com/pages/publications/0344780826

U2 - 10.1128/jb.181.12.3833-3836.1999

DO - 10.1128/jb.181.12.3833-3836.1999

M3 - Article

C2 - 10368161

AN - SCOPUS:0344780826

SN - 0021-9193

VL - 181

SP - 3833

EP - 3836

JO - Journal of Bacteriology

JF - Journal of Bacteriology

IS - 12

ER -

Role for the oxyS gene in regulation of intracellular hydrogen peroxide in Escherichia coli

Abstract

Access to Document

Other files and links

Fingerprint

Cite this