Skip to main navigation Skip to search Skip to main content

Semi-supervised Contrastive VAE for Disentanglement of Digital Pathology Images

  • Stony Brook University
  • Harvard University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Despite the strong prediction power of deep learning models, their interpretability remains an important concern. Disentanglement models increase interpretability by decomposing the latent space into interpretable subspaces. In this paper, we propose the first disentanglement method for pathology images. We focus on the task of detecting tumor-infiltrating lymphocytes (TIL). We propose different ideas including cascading disentanglement, novel architecture, and reconstruction branches. We achieve superior performance on complex pathology images, thus improving the interpretability and even generalization power of TIL detection deep learning models. Our codes are available at https://github.com/Shauqi/SS-cVAE.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention – MICCAI 2024 - 27th International Conference, Proceedings
EditorsMarius George Linguraru, Qi Dou, Aasa Feragen, Stamatia Giannarou, Ben Glocker, Karim Lekadir, Julia A. Schnabel
PublisherSpringer Science and Business Media Deutschland GmbH
Pages459-469
Number of pages11
ISBN (Print)9783031720826
DOIs
StatePublished - 2024
Event27th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2024 - Marrakesh, Morocco
Duration: Oct 6 2024Oct 10 2024

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume15004 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference27th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2024
Country/TerritoryMorocco
CityMarrakesh
Period10/6/2410/10/24

Keywords

  • Contrastive VAE
  • Digital Pathology
  • Disentanglement

Fingerprint

Dive into the research topics of 'Semi-supervised Contrastive VAE for Disentanglement of Digital Pathology Images'. Together they form a unique fingerprint.

Cite this