Sending protein aggregates into a downward spiral

Steven E. Glynn; Peter Chien

doi:10.1038/nsmb.3288

Sending protein aggregates into a downward spiral

Steven E. Glynn
, Peter Chien

Biochemistry and Cell Biology

University of Massachusetts

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

Cells deploy the Hsp100 family of ATP-dependent machines to work with cellular chaperones in dismantling dangerous protein aggregates. New studies reveal an unprecedented spiral structure that provides mechanistic insight into the protein disaggregase Hsp104.

Original language	English
Pages (from-to)	769-770
Number of pages	2
Journal	Nature Structural and Molecular Biology
Volume	23
Issue number	9
DOIs	https://doi.org/10.1038/nsmb.3288
State	Published - Sep 1 2016

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title = "Sending protein aggregates into a downward spiral",

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AU - Chien, Peter

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JO - Nature Structural and Molecular Biology

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Sending protein aggregates into a downward spiral

Abstract

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