@inproceedings{13c188821ed24a2ea476a3d4c07ee5e4,
title = "Single-cell detection of cytokines using a simple nanowell chip integrated with encoded microarray",
abstract = "Multiparameter analysis of individual immune cell's cytokine secretion has always been a challenging and complicated process that needs special facilities in a laboratory setting. Herein, we present an ultra-simple method with high sensitivity and high robustness to quantify cytokine expression at the single-cell resolution. A microchip with nanowell is integrated with a DNA-antibody convertible microarray. The sensitivity of the assay was found comparable to conventional methods. It has simplified a typically sophisticated multiplex single-cell assay into an instrument-free, point-of-detection technology, and thus it may find a broad utility in clinical diagnostics.",
keywords = "Microchip, Multiplex, Point-of-care diagnosis, Simple method, Single-cell analysis",
author = "Mohammed Abdullah and Jun Wang",
note = "Publisher Copyright: {\textcopyright} 2019 CBMS-0001.; 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 ; Conference date: 27-10-2019 Through 31-10-2019",
year = "2019",
language = "English",
series = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019",
publisher = "Chemical and Biological Microsystems Society",
pages = "474--475",
booktitle = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019",
}