Spike discrimination using amplitude measurements with a low-power CMOS neural amplifier

Timothy Horiuchi; Dorielle Tucker; Kevin Boyle; Pamela Abshire

doi:10.1109/iscas.2007.378092

Spike discrimination using amplitude measurements with a low-power CMOS neural amplifier

Timothy Horiuchi
, Dorielle Tucker
, Kevin Boyle
, Pamela Abshire

Electrical Engineering

University of Maryland, College Park
University of South Florida
Massachusetts Institute of Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2 Scopus citations

Abstract

Integrated CMOS neural amplifiers have recently grown in importance as large microelectrode arrays have begun to be practical. We previously reported low-power neural amplifiers with integrated pre-filtering and measurements of the spike signal to reduce data bandwidth and to facilitate spike-sorting prior to transmission to a data-acquisition system. Characteristics of a prototype circuit were reported using a 1.5 V power supply, suitable for single cell battery operation. Here we report improved transient amplitude tracking as well as application of the circuit in live recordings of wide-field motion sensitive cells in blowflies. The features extracted by the chip efficiently discriminate between stimulus conditions, as demonstrated by receiver operating characteristic analysis.

Original language	English
Title of host publication	2007 IEEE International Symposium on Circuits and Systems, ISCAS 2007
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	3123-3126
Number of pages	4
ISBN (Print)	1424409209
DOIs	https://doi.org/10.1109/iscas.2007.378092
State	Published - 2007
Event	2007 IEEE International Symposium on Circuits and Systems, ISCAS 2007 - New Orleans, LA, United States Duration: May 27 2007 → May 30 2007

Publication series

Name	Proceedings - IEEE International Symposium on Circuits and Systems
ISSN (Print)	0271-4310

Conference

Conference	2007 IEEE International Symposium on Circuits and Systems, ISCAS 2007
Country/Territory	United States
City	New Orleans, LA
Period	05/27/07 → 05/30/07

Access to Document

10.1109/iscas.2007.378092

Cite this

Horiuchi, T., Tucker, D., Boyle, K., & Abshire, P. (2007). Spike discrimination using amplitude measurements with a low-power CMOS neural amplifier. In 2007 IEEE International Symposium on Circuits and Systems, ISCAS 2007 (pp. 3123-3126). Article 4253340 (Proceedings - IEEE International Symposium on Circuits and Systems). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/iscas.2007.378092

@inproceedings{bf08fc8ed51740dfa0a242747bed1a03,

title = "Spike discrimination using amplitude measurements with a low-power CMOS neural amplifier",

abstract = "Integrated CMOS neural amplifiers have recently grown in importance as large microelectrode arrays have begun to be practical. We previously reported low-power neural amplifiers with integrated pre-filtering and measurements of the spike signal to reduce data bandwidth and to facilitate spike-sorting prior to transmission to a data-acquisition system. Characteristics of a prototype circuit were reported using a 1.5 V power supply, suitable for single cell battery operation. Here we report improved transient amplitude tracking as well as application of the circuit in live recordings of wide-field motion sensitive cells in blowflies. The features extracted by the chip efficiently discriminate between stimulus conditions, as demonstrated by receiver operating characteristic analysis.",

author = "Timothy Horiuchi and Dorielle Tucker and Kevin Boyle and Pamela Abshire",

year = "2007",

doi = "10.1109/iscas.2007.378092",

language = "English",

isbn = "1424409209",

series = "Proceedings - IEEE International Symposium on Circuits and Systems",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "3123--3126",

booktitle = "2007 IEEE International Symposium on Circuits and Systems, ISCAS 2007",

note = "2007 IEEE International Symposium on Circuits and Systems, ISCAS 2007 ; Conference date: 27-05-2007 Through 30-05-2007",

}

Horiuchi, T, Tucker, D, Boyle, K & Abshire, P 2007, Spike discrimination using amplitude measurements with a low-power CMOS neural amplifier. in 2007 IEEE International Symposium on Circuits and Systems, ISCAS 2007., 4253340, Proceedings - IEEE International Symposium on Circuits and Systems, Institute of Electrical and Electronics Engineers Inc., pp. 3123-3126, 2007 IEEE International Symposium on Circuits and Systems, ISCAS 2007, New Orleans, LA, United States, 05/27/07. https://doi.org/10.1109/iscas.2007.378092

Spike discrimination using amplitude measurements with a low-power CMOS neural amplifier. / Horiuchi, Timothy; Tucker, Dorielle; Boyle, Kevin et al.
2007 IEEE International Symposium on Circuits and Systems, ISCAS 2007. Institute of Electrical and Electronics Engineers Inc., 2007. p. 3123-3126 4253340 (Proceedings - IEEE International Symposium on Circuits and Systems).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Spike discrimination using amplitude measurements with a low-power CMOS neural amplifier

AU - Horiuchi, Timothy

AU - Tucker, Dorielle

AU - Boyle, Kevin

AU - Abshire, Pamela

PY - 2007

Y1 - 2007

N2 - Integrated CMOS neural amplifiers have recently grown in importance as large microelectrode arrays have begun to be practical. We previously reported low-power neural amplifiers with integrated pre-filtering and measurements of the spike signal to reduce data bandwidth and to facilitate spike-sorting prior to transmission to a data-acquisition system. Characteristics of a prototype circuit were reported using a 1.5 V power supply, suitable for single cell battery operation. Here we report improved transient amplitude tracking as well as application of the circuit in live recordings of wide-field motion sensitive cells in blowflies. The features extracted by the chip efficiently discriminate between stimulus conditions, as demonstrated by receiver operating characteristic analysis.

AB - Integrated CMOS neural amplifiers have recently grown in importance as large microelectrode arrays have begun to be practical. We previously reported low-power neural amplifiers with integrated pre-filtering and measurements of the spike signal to reduce data bandwidth and to facilitate spike-sorting prior to transmission to a data-acquisition system. Characteristics of a prototype circuit were reported using a 1.5 V power supply, suitable for single cell battery operation. Here we report improved transient amplitude tracking as well as application of the circuit in live recordings of wide-field motion sensitive cells in blowflies. The features extracted by the chip efficiently discriminate between stimulus conditions, as demonstrated by receiver operating characteristic analysis.

UR - https://www.scopus.com/pages/publications/34548850628

U2 - 10.1109/iscas.2007.378092

DO - 10.1109/iscas.2007.378092

M3 - Conference contribution

AN - SCOPUS:34548850628

SN - 1424409209

T3 - Proceedings - IEEE International Symposium on Circuits and Systems

SP - 3123

EP - 3126

BT - 2007 IEEE International Symposium on Circuits and Systems, ISCAS 2007

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2007 IEEE International Symposium on Circuits and Systems, ISCAS 2007

Y2 - 27 May 2007 through 30 May 2007

ER -

Horiuchi T, Tucker D, Boyle K, Abshire P. Spike discrimination using amplitude measurements with a low-power CMOS neural amplifier. In 2007 IEEE International Symposium on Circuits and Systems, ISCAS 2007. Institute of Electrical and Electronics Engineers Inc. 2007. p. 3123-3126. 4253340. (Proceedings - IEEE International Symposium on Circuits and Systems). doi: 10.1109/iscas.2007.378092

Spike discrimination using amplitude measurements with a low-power CMOS neural amplifier

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