Steroids I. Alkylation of β-ketoesters via their Cu(II) enolates in aqueous media. Application of the synthesis of C-18 functionalized steroids via the torgov approach.

Plato A. Magriotis; William V. Murray; Francis Johnson

doi:10.1016/S0040-4039(00)87242-1

Steroids I. Alkylation of β-ketoesters via their Cu(II) enolates in aqueous media. Application of the synthesis of C-18 functionalized steroids via the torgov approach.

Plato A. Magriotis
, William V. Murray
, Francis Johnson

Pharmacological Sciences

Stony Brook University

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Three steroidal pentaenes (8a-c0 have been synthesized, the key step being the alkylation of the Cu(II) chelates to the ring D precursors (3-5) by the isothiouronium acetate 1 in aqueous solution.

Original language	English
Pages (from-to)	1993-1996
Number of pages	4
Journal	Tetrahedron Letters
Volume	23
Issue number	19
DOIs	https://doi.org/10.1016/S0040-4039(00)87242-1
State	Published - 1982

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@article{76e8358bd1124595a643f1e6233fa8cc,

title = "Steroids I. Alkylation of β-ketoesters via their Cu(II) enolates in aqueous media. Application of the synthesis of C-18 functionalized steroids via the torgov approach.",

abstract = "Three steroidal pentaenes (8a-c0 have been synthesized, the key step being the alkylation of the Cu(II) chelates to the ring D precursors (3-5) by the isothiouronium acetate 1 in aqueous solution.",

author = "Magriotis, \{Plato A.\} and Murray, \{William V.\} and Francis Johnson",

year = "1982",

doi = "10.1016/S0040-4039(00)87242-1",

language = "English",

volume = "23",

pages = "1993--1996",

journal = "Tetrahedron Letters",

issn = "0040-4039",

number = "19",

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TY - JOUR

T1 - Steroids I. Alkylation of β-ketoesters via their Cu(II) enolates in aqueous media. Application of the synthesis of C-18 functionalized steroids via the torgov approach.

AU - Magriotis, Plato A.

AU - Murray, William V.

AU - Johnson, Francis

PY - 1982

Y1 - 1982

N2 - Three steroidal pentaenes (8a-c0 have been synthesized, the key step being the alkylation of the Cu(II) chelates to the ring D precursors (3-5) by the isothiouronium acetate 1 in aqueous solution.

AB - Three steroidal pentaenes (8a-c0 have been synthesized, the key step being the alkylation of the Cu(II) chelates to the ring D precursors (3-5) by the isothiouronium acetate 1 in aqueous solution.

UR - https://www.scopus.com/pages/publications/0343724202

U2 - 10.1016/S0040-4039(00)87242-1

DO - 10.1016/S0040-4039(00)87242-1

M3 - Article

AN - SCOPUS:0343724202

SN - 0040-4039

VL - 23

SP - 1993

EP - 1996

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 19

ER -

Steroids I. Alkylation of β-ketoesters via their Cu(II) enolates in aqueous media. Application of the synthesis of C-18 functionalized steroids via the torgov approach.

Abstract

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