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Stochastic modeling of second order reactions using a moment propagation method

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Abstract

The traditional methods for solving the chemical master equation are based on Monte Carlo methods, such as the stochastic simulation algorithm (SSA) and its accelerated versions. Methods for modeling biochemical networks based on moment propagation are a relatively unexplored area. In a prior paper, we addressed first-order reactions and presented a new method for propagating the first two moments of the probability distributions of the number of molecules over time. In this paper we extend this method to second order reactions and demonstrate its performance on some simple networks.

Original languageEnglish
Title of host publication2009 IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS 2009
DOIs
StatePublished - 2009
Event2009 IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS 2009 - Minneapolis, MN, United States
Duration: May 17 2009May 21 2009

Publication series

Name2009 IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS 2009

Conference

Conference2009 IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS 2009
Country/TerritoryUnited States
CityMinneapolis, MN
Period05/17/0905/21/09

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