Study of the FMRI blood oxygen level dependent effect by near-infrared spectroscopy

Vlad Toronov; Andrew Webb; Scott Walker; Rajarsi Gupta; Jee H. Choi; Enrico Gratton; Dennis Hueber

Study of the FMRI blood oxygen level dependent effect by near-infrared spectroscopy

Vlad Toronov
, Andrew Webb
, Scott Walker
, Rajarsi Gupta
, Jee H. Choi
, Enrico Gratton
, Dennis Hueber

Biomedical Informatics

University of Illinois at Urbana-Champaign
ISS Inc.

Research output: Contribution to journal › Conference article › peer-review

Abstract

In order to study the behavior of cerebral physiological parameters and to further the understanding of the fMRI blood-oxygen-level-dependent (BOLD) effect, we have recorded simultaneously multi-source frequency-domain near-infrared and BOLD fMRI signals during motor functional activation in humans. From the near-infrared data we obtained information on the changes in cerebral blood volume and oxygenation. In order to relate our observations to changes in cerebral blood flow we employed the "balloon" model of cerebral perfusion. Our data showed that the deoxyhemoglobin concentration is the major factor determining the time course of the BOLD signal.

Original language	English
Pages (from-to)	222-226
Number of pages	5
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	5068
State	Published - 2002
Event	Saratov Fall Meeting 2002 Optical Technologies in Biophysics and Medicine IV - Saratov, Russian Federation Duration: Oct 1 2002 → Oct 4 2002

Cite this

@article{40292f85ca0e4053974f065486eb0197,

title = "Study of the FMRI blood oxygen level dependent effect by near-infrared spectroscopy",

abstract = "In order to study the behavior of cerebral physiological parameters and to further the understanding of the fMRI blood-oxygen-level-dependent (BOLD) effect, we have recorded simultaneously multi-source frequency-domain near-infrared and BOLD fMRI signals during motor functional activation in humans. From the near-infrared data we obtained information on the changes in cerebral blood volume and oxygenation. In order to relate our observations to changes in cerebral blood flow we employed the {"}balloon{"} model of cerebral perfusion. Our data showed that the deoxyhemoglobin concentration is the major factor determining the time course of the BOLD signal.",

author = "Vlad Toronov and Andrew Webb and Scott Walker and Rajarsi Gupta and Choi, \{Jee H.\} and Enrico Gratton and Dennis Hueber",

year = "2002",

language = "English",

volume = "5068",

pages = "222--226",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

issn = "0277-786X",

note = "Saratov Fall Meeting 2002 Optical Technologies in Biophysics and Medicine IV ; Conference date: 01-10-2002 Through 04-10-2002",

}

TY - JOUR

T1 - Study of the FMRI blood oxygen level dependent effect by near-infrared spectroscopy

AU - Toronov, Vlad

AU - Webb, Andrew

AU - Walker, Scott

AU - Gupta, Rajarsi

AU - Choi, Jee H.

AU - Gratton, Enrico

AU - Hueber, Dennis

PY - 2002

Y1 - 2002

N2 - In order to study the behavior of cerebral physiological parameters and to further the understanding of the fMRI blood-oxygen-level-dependent (BOLD) effect, we have recorded simultaneously multi-source frequency-domain near-infrared and BOLD fMRI signals during motor functional activation in humans. From the near-infrared data we obtained information on the changes in cerebral blood volume and oxygenation. In order to relate our observations to changes in cerebral blood flow we employed the "balloon" model of cerebral perfusion. Our data showed that the deoxyhemoglobin concentration is the major factor determining the time course of the BOLD signal.

AB - In order to study the behavior of cerebral physiological parameters and to further the understanding of the fMRI blood-oxygen-level-dependent (BOLD) effect, we have recorded simultaneously multi-source frequency-domain near-infrared and BOLD fMRI signals during motor functional activation in humans. From the near-infrared data we obtained information on the changes in cerebral blood volume and oxygenation. In order to relate our observations to changes in cerebral blood flow we employed the "balloon" model of cerebral perfusion. Our data showed that the deoxyhemoglobin concentration is the major factor determining the time course of the BOLD signal.

UR - https://www.scopus.com/pages/publications/1342289445

M3 - Conference article

AN - SCOPUS:1342289445

SN - 0277-786X

VL - 5068

SP - 222

EP - 226

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Saratov Fall Meeting 2002 Optical Technologies in Biophysics and Medicine IV

Y2 - 1 October 2002 through 4 October 2002

ER -

Study of the FMRI blood oxygen level dependent effect by near-infrared spectroscopy

Abstract

Other files and links

Fingerprint

Cite this