Substance use disorders and disorders of mood

Epidemiological surveys and clinical studies consistently suggest that mood and substance use disorders are among the most prevalent forms of psychopathology. Research also indicates that the cooccurrence of these disorders is exceptionally common. Efforts to better characterize and understand the factors underlying high comorbidity rates between mood and substance use disorders are crucial given links to negative outcomes for individuals afflicted with both disorders. This chapter draws upon the extant literature regarding the prevalence, consequences, etiology, and dynamic nature of comorbid mood and substance use disorders, and highlights key issues in a case illustration. The chapter concludes with a discussion of gaps in the literature, as well as consideration of the pragmatic and clinical implications surrounding this particular comorbidity.