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Supression of newborn natural killer cell activity by prostaglandin E2

  • Stony Brook University

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The effect of prostaglandin E2 on natural killer cell activity of cord blood was examined. Natural killer cell activity, determined by chromium 51 release, was significantly reduced after prostaglandin E2 (1 μg/ml) treatment. Prostaglandin E2 has been found to enhance the cellular spread of herpesvirus. Thus prostaglandins may enhance viral infections indirectly by suppressing natural killer cell activity.

Original languageEnglish
Pages (from-to)895-896
Number of pages2
JournalAmerican Journal of Obstetrics and Gynecology
Volume159
Issue number4
DOIs
StatePublished - 1988

Keywords

  • Herpesvirus
  • natural killer cell activity
  • prostaglandin

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