Suspicious for Malignancy

Esther Diana Rossi; Syed Ali; Claude Bigorgne; Ashish Chandra; Yun Gong; Daniel Lubin; Renata B. Perak; Bo Ping; He Wang; Matthew Zarka

doi:10.1007/978-3-031-26662-1_6

Suspicious for Malignancy

Esther Diana Rossi
, Syed Ali
, Claude Bigorgne
, Ashish Chandra
, Yun Gong
, Daniel Lubin
, Renata B. Perak
, Bo Ping
, He Wang
, Matthew Zarka

Pathology

Fondazione Policlinico Universitario A.Gemelli IRCS
Johns Hopkins University
Cytopathology and Imaging Center
Guy's and St Thomas' NHS Foundation Trust
University of Texas MD Anderson Cancer Center
Emory University
University of Split
Fudan University
Mayo Clinic Scottsdale-Phoenix, Arizona

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The Suspicious for Malignancy (SM) category is a traditional diagnostic category used in nearly all cytology reporting systems, and, as such, its characteristics are well known to practicing cytologists. The purpose of separating the SM from the Malignant category is to preserve the high positive predictive value (PPV) of an FNA classified as malignant while at the same time offering a diagnostic option with a relatively high ROM for those FNAs where the cytomorphologic criteria fall short in quantity and/or quality for a malignant interpretation. In the second edition of the Milan System, the ROM for the SM category is 83%. With the growing availability of immunohistochemical and molecular markers for salivary gland tumors, a subset of FNAs classified as SM may benefit from the application of ancillary testing to yield a more specific interpretation.

Original language	English
Title of host publication	The Milan System for Reporting Salivary Gland Cytopathology, Second Edition
Publisher	Springer International Publishing
Pages	105-115
Number of pages	11
ISBN (Electronic)	9783031266621
ISBN (Print)	9783031266614
DOIs	https://doi.org/10.1007/978-3-031-26662-1_6
State	Published - Jan 1 2023

Keywords

Carcinoma
FNA
Lymphoma
Risk of malignancy
Salivary gland
Suspicious for malignancy

Access to Document

10.1007/978-3-031-26662-1_6

Cite this

@inbook{06e759d3345b4fabab2ecaa2fba9e516,

title = "Suspicious for Malignancy",

abstract = "The Suspicious for Malignancy (SM) category is a traditional diagnostic category used in nearly all cytology reporting systems, and, as such, its characteristics are well known to practicing cytologists. The purpose of separating the SM from the Malignant category is to preserve the high positive predictive value (PPV) of an FNA classified as malignant while at the same time offering a diagnostic option with a relatively high ROM for those FNAs where the cytomorphologic criteria fall short in quantity and/or quality for a malignant interpretation. In the second edition of the Milan System, the ROM for the SM category is 83\%. With the growing availability of immunohistochemical and molecular markers for salivary gland tumors, a subset of FNAs classified as SM may benefit from the application of ancillary testing to yield a more specific interpretation.",

keywords = "Carcinoma, FNA, Lymphoma, Risk of malignancy, Salivary gland, Suspicious for malignancy",

author = "Rossi, \{Esther Diana\} and Syed Ali and Claude Bigorgne and Ashish Chandra and Yun Gong and Daniel Lubin and Perak, \{Renata B.\} and Bo Ping and He Wang and Matthew Zarka",

note = "Publisher Copyright: {\textcopyright} American Society of Cytopathology 2023.",

year = "2023",

month = jan,

day = "1",

doi = "10.1007/978-3-031-26662-1\_6",

language = "English",

isbn = "9783031266614",

pages = "105--115",

booktitle = "The Milan System for Reporting Salivary Gland Cytopathology, Second Edition",

publisher = "Springer International Publishing",

}

TY - CHAP

T1 - Suspicious for Malignancy

AU - Rossi, Esther Diana

AU - Ali, Syed

AU - Bigorgne, Claude

AU - Chandra, Ashish

AU - Gong, Yun

AU - Lubin, Daniel

AU - Perak, Renata B.

AU - Ping, Bo

AU - Wang, He

AU - Zarka, Matthew

N1 - Publisher Copyright: © American Society of Cytopathology 2023.

PY - 2023/1/1

Y1 - 2023/1/1

N2 - The Suspicious for Malignancy (SM) category is a traditional diagnostic category used in nearly all cytology reporting systems, and, as such, its characteristics are well known to practicing cytologists. The purpose of separating the SM from the Malignant category is to preserve the high positive predictive value (PPV) of an FNA classified as malignant while at the same time offering a diagnostic option with a relatively high ROM for those FNAs where the cytomorphologic criteria fall short in quantity and/or quality for a malignant interpretation. In the second edition of the Milan System, the ROM for the SM category is 83%. With the growing availability of immunohistochemical and molecular markers for salivary gland tumors, a subset of FNAs classified as SM may benefit from the application of ancillary testing to yield a more specific interpretation.

AB - The Suspicious for Malignancy (SM) category is a traditional diagnostic category used in nearly all cytology reporting systems, and, as such, its characteristics are well known to practicing cytologists. The purpose of separating the SM from the Malignant category is to preserve the high positive predictive value (PPV) of an FNA classified as malignant while at the same time offering a diagnostic option with a relatively high ROM for those FNAs where the cytomorphologic criteria fall short in quantity and/or quality for a malignant interpretation. In the second edition of the Milan System, the ROM for the SM category is 83%. With the growing availability of immunohistochemical and molecular markers for salivary gland tumors, a subset of FNAs classified as SM may benefit from the application of ancillary testing to yield a more specific interpretation.

KW - Carcinoma

KW - FNA

KW - Lymphoma

KW - Risk of malignancy

KW - Salivary gland

KW - Suspicious for malignancy

UR - https://www.scopus.com/pages/publications/85173408571

U2 - 10.1007/978-3-031-26662-1_6

DO - 10.1007/978-3-031-26662-1_6

M3 - Chapter

AN - SCOPUS:85173408571

SN - 9783031266614

SP - 105

EP - 115

BT - The Milan System for Reporting Salivary Gland Cytopathology, Second Edition

PB - Springer International Publishing

ER -

Suspicious for Malignancy

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this